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Yewseok Suh
Researcher at University of Wisconsin-Madison
Publications - 13
Citations - 1134
Yewseok Suh is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Cell growth & Apoptosis. The author has an hindex of 10, co-authored 12 publications receiving 1026 citations.
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A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-κB-signaling pathways
TL;DR: Evidence is provided that the plant flavonoid fisetin can induce apoptosis and suppress the growth of colon cancer cells by inhibition of COX2- and Wnt/EGFR/NF-kappaB-signaling pathways.
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Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells
TL;DR: Evidence is provided that fisetin functions as a dual inhibitor of mTORC1/2 signaling leading to inhibition of Cap-dependent translation and induction of autophagic cell death in PC3 cells, suggesting that f isetin could be a useful chemotherapeutic agent in treatment of hormone refractory CaP.
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Dual inhibition of phosphatidylinositol 3‐kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin
TL;DR: The results show that fisetin suppressed PI3K/Akt and mTOR signaling in NSCLC cells and thus, could be developed as a chemotherapeutic agent against human lung cancer.
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Lupeol inhibits growth of highly aggressive human metastatic melanoma cells in vitro and in vivo by inducing apoptosis.
Mohammad Saleem,Nityanand Maddodi,Mohammad Abu Zaid,Naghma Khan,Bilal Bin Hafeez,Mohammad Asim,Yewseok Suh,Jung-Mi Yun,Vijayasaradhi Setaluri,Hasan Mukhtar +9 more
TL;DR: It is suggested that lupeol, alone or as an adjuvant to current therapies, could be useful for the management of human melanoma.
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Dietary agents for chemoprevention of prostate cancer
TL;DR: The findings from clinical and preclinical studies on dietary agents including green tea, pomegranate, lupeol, fisetin, and delphinidin that are currently being investigated in the laboratory for their chemopreventive potential against CaP are summarized.