Yhiya Amen

TL;DR: Seven compounds from olive mill wastes are isolated and investigated their antidiabetic potential through inhibition of α-glucosidase and α-amylase enzymes, one of them being novel, and it is shown that the esterification of C-1 of the furofuran ring is the key feature for the stronger activity of 1-acetoxypinoresinol 3 against both enzymes.

TL;DR: Two compounds have been identified as potent and selective cytotoxic agents against HeLa and MCF-7 cell lines and are highlighted as a promising class of compounds for further studies concerning new anticancer therapies.

TL;DR: Among the compounds, lucidumol C showed potent selective cytotoxicity against HCT-116 cells with an IC50 value of 7.86 ± 4.56 µM and selectivity index (SI) >10 with remarkable cytotoxic activities against Caco-2, HepG2 and HeLa cell lines.

TL;DR: The structure-activity relationship indicated that carbonyl function at C-11 is necessary to enhance the cytotoxicity of lucidumol D against proliferation of several cancer cells.

TL;DR: The results of this study suggested the potential use of Coix lacryma-jobi seeds as a skin whitening agent and reveal the seeds to be a rich source of important phytochemicals with melanogenesis inhibitory activity.