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Yi Li

Researcher at Academy of Military Medical Sciences

Publications -  7
Citations -  242

Yi Li is an academic researcher from Academy of Military Medical Sciences. The author has contributed to research in topics: Virus & Vaccinia. The author has an hindex of 6, co-authored 7 publications receiving 203 citations.

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In vitro evaluation of the probiotic and functional potential of Lactobacillus strains isolated from fermented food and human intestine.

TL;DR: Although a wide variation in the ability of the eight strains to deplete cholesterol and nitrite, antagonize pathogens, scavenge free radical, and stimulate innate immune response were observed, the strains CICC 23174 and CGMCC 1.557 exhibited the best probiotic properties with the potential for use in the production of probiotic fermented foods.
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Inhibition of Staphylococcus aureus adherence to Caco-2 cells by lactobacilli and cell surface properties that influence attachment.

TL;DR: Lactobacillus salivarius and L. plantarum strongly inhibited S. aureus adherence to Caco-2 cells and their inhibition activity was significantly influenced by several factors that affect adhesion inhibition.
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The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection

TL;DR: Investigation of the antiviral activities and mechanisms of interferon-inducible transmembrane protein 3 (IFITM3) protein against poxvirus infection provides the first evidence of exogenously expressed IFITm3 protein restricting infection of an enveloped DNA virus, thus expanding their antiviral spectrum.
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Protection against SHIV-KB9 Infection by Combining rDNA and rFPV Vaccines Based on HIV Multiepitope and p24 Protein in Chinese Rhesus Macaques

TL;DR: Results show that, upon challenge, the vaccine group can induce a strong immune response in the body, represented by increased expression of IFN-γ, slow and steady elevated antibody production, reduced peak value of acute viral load, and increase in the average CD4/CD8 ratio.
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Immunogenicity analysis following human immunodeficiency virus recombinant DNA and recombinant vaccinia virus Tian Tan prime-boost immunization.

TL;DR: It is demonstrated that prime-boost immunization with rDNA and rddVTT-CCMp24 had a tendency to induce greater cellular immune response than single-shot vaccinations, especially IFN-γ response, providing a basis for further studies.