Yidan Sun

TL;DR: Electrochromic materials are engineering of an organic π-electron structure-based EM as a unique hydrogen sulfide (H2S)-responsive chromophore amenable to build H2S-activatable fluorescent probes ( 12+-semiconducting polymer nanoparticles, 12+-SNPs) for in vivo H 2S detection.

TL;DR: An afterglow nanoparticle which is activated by hydrogen sulphide is reported on and the measurement of hydrogen sulphides levels and the labelling of hepatic cancer specimens in vivo are demonstrated.

TL;DR: A tumor-targeted and matrix metalloprotease-2 -activatable nanoprobe formed by covalent modification of Gd-doping CuS micellar nanoparticles with cRGD and an MMP-2-cleavable fluorescent substrate is reported, allowing high-spatial-resolution magnetic resonance imaging (MRI) and low-background fluorescence imaging of gastric tumors as well as lymph node (LN) metastasis in living mice.

TL;DR: A new fluorescent copper sulfide (CuS) nanoparticle (RGD-CuS-Cy5.5) enabling both non-invasive multimodality imaging and targeting photothermal therapy (PTT) of metastatic gastric cancer cells in lymph nodes is reported, which may be applicable for the metastatic Gastric cancer therapy in clinics.

TL;DR: A tumor targeting and adenosine triphosphate-activatable nanophotosensitizer Apt-HyNP/BHQ2 is reported by modifying hybrid micellar nanoparticles with both nucleolin-targeting aptamer AS1411 and quencher B HQ2-labeled ATP-binding aptamer BHQ2-ATP-apt, allowing for selective ablation of tumors without obvious side effects.