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Yih Gang Goan

Researcher at National Yang-Ming University

Publications -  5
Citations -  430

Yih Gang Goan is an academic researcher from National Yang-Ming University. The author has contributed to research in topics: Carcinogenesis & microRNA. The author has an hindex of 5, co-authored 5 publications receiving 408 citations.

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Journal ArticleDOI

MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation

TL;DR: This is the first study to show that E2F1 is negatively regulated by miR-330 and also show that miR -330 induces apoptosis in prostate cancer cells through E1F1-mediated suppression of Akt phosphorylation.
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MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer.

TL;DR: It is shown that miR-373 would be a potential oncogene and it participates in the carcinogenesis of human esophageal cancer by suppressing LATS2 expression and this correlation was supported by data collected ex vivo, in which esophagal cancer tissues from esphageal squamous cell carcinoma patients were analyzed.
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Alpha-actinin 4 is associated with cancer cell motility and is a potential biomarker in non-small cell lung cancer.

TL;DR: The results suggest that ACTn4 is associated with lung cancer cell motility, and the level of ACTN4 in cancerous tissue and plasma is related to the presence of lung cancer.
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Qualification and Verification of Serological Biomarker Candidates for Lung Adenocarcinoma by Targeted Mass Spectrometry.

TL;DR: The results highlighted several possible markers for lung adenocarcinoma, and the proposed protein panels require further validation in a larger cohort to evaluate their potential use in clinical applications or development of therapeutics.
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Pin1 positively affects tumorigenesis of esophageal squamous cell carcinoma and correlates with poor survival of patients

TL;DR: Results indicated that targeting Pin1 pathway could represent a potential modality for treating ESCC and that high Pin1 expression was associated with advanced stage and poor prognosis of ESCC.