Shauh-Der Yeh

TL;DR: This is the first study to show that E2F1 is negatively regulated by miR-330 and also show that miR -330 induces apoptosis in prostate cancer cells through E1F1-mediated suppression of Akt phosphorylation.

TL;DR: Results support that miR-320 is a key negative regulator in prostate TICs, and suggest developing mi R-320 as a novel therapeutic agent may offer benefits for PCa treatment.

TL;DR: The results indicate that Azoospermia Factor c partial deletion and partial duplication are common polymorphisms in Han Chinese, and that the AZFc partial duplication, but not the AZfc partial deletion, is a risk factor for male infertility in the Taiwanese population.

TL;DR: The findings indicate that loss of function of DUSP22 in PCa cells leads to aberrant activation of both EGFR‐ERKs and AR signaling and ultimately progression of PCa, supporting the potential for novel therapeutic design of harnessing DUSp22 in the treatment ofPCa.

TL;DR: It is proposed that estrogen might be able to antagonize the folic acid-induced anti-angiogenesis activity, and this hypothesis has been proved.