Y
Ying Deng
Researcher at Sun Yat-sen University
Publications - 5
Citations - 111
Ying Deng is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Bilobalide & Ginkgo biloba. The author has an hindex of 4, co-authored 4 publications receiving 98 citations.
Papers
More filters
Journal ArticleDOI
Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in rats
Ying Deng,Huichang Bi,Li-zi Zhao,Fan He,Yizhi Liu,J.-J. Yu,Z.-M. Ou,Liang Ding,Xi Chen,Zhiying Huang,Min Huang,Shu-Feng Zhou +11 more
TL;DR: The results indicate that bilobalide, and to a lesser extent ginkgolide A, B, quercetin, and kaempferol, play a key role in the effects of EGb 761 on CYP induction.
Journal ArticleDOI
Induction of Cytochrome P450 3A by the Ginkgo biloba Extract and Bilobalides in Human and Rat Primary Hepatocytes
Ying Deng,Huichang Bi,Li-zi Zhao,Xueding Wang,Jie Chen,Zhimin Ou,Liang Ding,Le-jia Xu,Su Guan,Xiao Chen,Shu-Feng Zhou,Min Huang +11 more
TL;DR: Investigation of the activity and expression of cytochrome P450 (CYP) 3A in human and rat primary hepatocytes treated with standardized G. biloba extract and ginkgolide suggests that bilobalide might play a key role in the enzyme-inducing effects of G.biloba extract.
Journal ArticleDOI
Determination of levonorgestrel in human plasma by liquid chromatography–tandem mass spectrometry method: application to a bioequivalence study of two formulations in healthy volunteers
Li-zi Zhao,Guoping Zhong,Huichang Bi,Liang Ding,Ying Deng,Su Guan,Xiao Chen,Zhiying Huang,Min Huang +8 more
TL;DR: The validated LC/MS/MS method was successfully used for a bioequivalence study of two tablet formulations of levonorgestrel in healthy volunteers and had high selectivity, acceptable accuracy, precision and sensitivity.
Journal ArticleDOI
Properties and Mechanisms of Flavin-Dependent Monooxygenases and Their Applications in Natural Product Synthesis
TL;DR: This review introduces the mechanisms for different FMOs, with the classical FAD (C4a)-hydroperoxide as the major oxidant, and summarizes the difference between F MOs and cytochrome P450 (CYP450) monooxygenases emphasizing the advantages of FMO's and their specificity for substrates.
Journal ArticleDOI
High‐throughput determination of carbocysteine in human plasma by liquid chromatography/tandem mass spectrometry: application to a bioequivalence study of two formulations in healthy volunteers
TL;DR: The validated LC/MS/MS method has been successfully used to a bioequivalence study of two tablet formulations of carbocysteine in healthy volunteers and had high selectivity, acceptable accuracy, precision and sensitivity.