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Yingfei Chen

Researcher at Iowa State University

Publications -  10
Citations -  1314

Yingfei Chen is an academic researcher from Iowa State University. The author has contributed to research in topics: Ketoacyl synthase & Medicine. The author has an hindex of 7, co-authored 8 publications receiving 1265 citations.

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The Universal Protein Resource (UniProt) in 2010

Rolf Apweiler, +133 more
Journal ArticleDOI

Thioesterases: a new perspective based on their primary and tertiary structures.

TL;DR: This work used strong primary sequence conservation based on experimentally proved proteins as the main criterion, followed by verification with tertiary structure superpositions, mechanisms, and catalytic residue positions, to accurately define TE families.
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Structural classification and properties of ketoacyl synthases

TL;DR: The classification of KSs by their primary and tertiary structures instead of by their substrates and the reactions that they catalyze enhances insights into this enzyme group.
Journal ArticleDOI

ThYme: a database for thioester-active enzymes

TL;DR: The ThYme (Thioester-active enzYme) database has been constructed to bring together amino acid sequences and 3D structures of all the enzymes constituting the fatty acid synthesis and polyketide synthesis cycles.
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Carboxylic ester hydrolases: Classification and database derived from their primary, secondary, and tertiary structures.

TL;DR: This work for the first time has fully established the carboxylic ester hydrolases into families and clans by use of multiple sequence alignments, secondary structure analysis, and tertiary structure superpositions.