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Yizhu Lin
Researcher at University of California, San Francisco
Publications - 5
Citations - 3729
Yizhu Lin is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Biology & Drug repositioning. The author has an hindex of 2, co-authored 2 publications receiving 2407 citations.
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Journal ArticleDOI
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
David E. Gordon,Gwendolyn M. Jang,Mehdi Bouhaddou,Jiewei Xu,Kirsten Obernier,Kris M. White,Matthew J. O’Meara,Veronica V. Rezelj,Jeffrey Z. Guo,Danielle L. Swaney,Tia A. Tummino,Ruth Hüttenhain,Robyn M. Kaake,Alicia L. Richards,Beril Tutuncuoglu,Helene Foussard,Jyoti Batra,Kelsey M. Haas,Maya Modak,Minkyu Kim,Paige Haas,Benjamin J. Polacco,Hannes Braberg,Jacqueline M. Fabius,Manon Eckhardt,Margaret Soucheray,Melanie J. Bennett,Merve Cakir,Michael McGregor,Qiongyu Li,Bjoern Meyer,Ferdinand Roesch,Thomas Vallet,Alice Mac Kain,Lisa Miorin,Elena Moreno,Zun Zar Chi Naing,Yuan Zhou,Shiming Peng,Ying Shi,Ziyang Zhang,Wenqi Shen,Ilsa T Kirby,James E. Melnyk,John S. Chorba,Kevin Lou,Shizhong Dai,Inigo Barrio-Hernandez,Danish Memon,Claudia Hernandez-Armenta,Jiankun Lyu,Christopher J.P. Mathy,Tina Perica,Kala Bharath Pilla,Sai J. Ganesan,Daniel J. Saltzberg,Rakesh Ramachandran,Xi Liu,Sara Brin Rosenthal,Lorenzo Calviello,Srivats Venkataramanan,Jose Liboy-Lugo,Yizhu Lin,Xi Ping Huang,Yongfeng Liu,Stephanie A. Wankowicz,Markus Bohn,Maliheh Safari,Fatima S. Ugur,Cassandra Koh,Nastaran Sadat Savar,Quang Dinh Tran,Djoshkun Shengjuler,Sabrina J. Fletcher,Michael C. O’Neal,Yiming Cai,Jason C.J. Chang,David J. Broadhurst,Saker Klippsten,Phillip P. Sharp,Nicole A. Wenzell,Duygu Kuzuoğlu-Öztürk,Hao-Yuan Wang,Raphael Trenker,Janet M. Young,Devin A. Cavero,Devin A. Cavero,Joseph Hiatt,Joseph Hiatt,Theodore L. Roth,Ujjwal Rathore,Ujjwal Rathore,Advait Subramanian,Julia Noack,Mathieu Hubert,Robert M. Stroud,Alan D. Frankel,Oren S. Rosenberg,Kliment A. Verba,David A. Agard,Melanie Ott,Michael Emerman,Natalia Jura,Mark von Zastrow,Eric Verdin,Eric Verdin,Alan Ashworth,Olivier Schwartz,Christophe d'Enfert,Shaeri Mukherjee,Matthew P. Jacobson,Harmit S. Malik,Danica Galonić Fujimori,Trey Ideker,Charles S. Craik,Stephen N. Floor,James S. Fraser,John D. Gross,Andrej Sali,Bryan L. Roth,Davide Ruggero,Jack Taunton,Tanja Kortemme,Pedro Beltrao,Marco Vignuzzi,Adolfo García-Sastre,Kevan M. Shokat,Brian K. Shoichet,Nevan J. Krogan +128 more
TL;DR: A human–SARS-CoV-2 protein interaction map highlights cellular processes that are hijacked by the virus and that can be targeted by existing drugs, including inhibitors of mRNA translation and predicted regulators of the sigma receptors.
Posted ContentDOI
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
David E. Gordon,Gwendolyn M. Jang,Mehdi Bouhaddou,Jiewei Xu,Kirsten Obernier,Jeffrey Z. Guo,Danielle L. Swaney,Tia A. Tummino,Tia A. Tummino,Ruth Hüttenhain,Robyn M. Kaake,Alicia L. Richards,Beril Tutuncuoglu,Helene Foussard,Jyoti Batra,Kelsey M. Haas,Maya Modak,Minkyu Kim,Paige Haas,Benjamin J. Polacco,Hannes Braberg,Jacqueline M. Fabius,Manon Eckhardt,Margaret Soucheray,Melanie J. Bennett,Merve Cakir,Michael McGregor,Qiongyu Li,Zun Zar Chi Naing,Yuan Zhou,Shiming Peng,Shiming Peng,Ilsa T Kirby,Ilsa T Kirby,James E. Melnyk,James E. Melnyk,John S. Chorba,John S. Chorba,Kevin Lou,Kevin Lou,Shizhong Dai,Shizhong Dai,Wenqi Shen,Wenqi Shen,Ying Shi,Ying Shi,Ziyang Zhang,Ziyang Zhang,Inigo Barrio-Hernandez,Danish Memon,Claudia Hernandez-Armenta,Christopher J.P. Mathy,Tina Perica,Tina Perica,Kala Bharath Pilla,Kala Bharath Pilla,Sai J. Ganesan,Sai J. Ganesan,Daniel J. Saltzberg,Daniel J. Saltzberg,Rakesh Ramachandran,Rakesh Ramachandran,Xi Liu,Xi Liu,Sara Brin Rosenthal,Lorenzo Calviello,Srivats Venkataramanan,Jose Liboy-Lugo,Yizhu Lin,Stephanie A. Wankowicz,Markus Bohn,Phillip P. Sharp,Raphael Trenker,Janet M. Young,Devin A. Cavero,Joseph Hiatt,Joseph Hiatt,Theodore L. Roth,Theodore L. Roth,Ujjwal Rathore,Advait Subramanian,Julia Noack,Mathieu Hubert,Ferdinand Roesch,Thomas Vallet,Bjoern Meyer,Kris M. White,Lisa Miorin,Oren S. Rosenberg,Kliment A. Verba,Kliment A. Verba,David A. Agard,Melanie Ott,Melanie Ott,Michael Emerman,Davide Ruggero,Davide Ruggero,Adolfo García-Sastre,Natalia Jura,Mark von Zastrow,Jack Taunton,Alan Ashworth,Olivier Schwartz,Marco Vignuzzi,Shaeri Mukherjee,Matthew P. Jacobson,Harmit S. Malik,Danica Galonić Fujimori,Danica Galonić Fujimori,Trey Ideker,Charles S. Craik,Stephen N. Floor,James S. Fraser,James S. Fraser,John D. Gross,John D. Gross,Andrej Sali,Tanja Kortemme,Pedro Beltrao,Kevan M. Shokat,Kevan M. Shokat,Brian K. Shoichet,Brian K. Shoichet,Nevan J. Krogan +123 more
TL;DR: The identification of host dependency factors mediating virus infection may provide key insights into effective molecular targets for developing broadly acting antiviral therapeutics against SARS-CoV-2 and other deadly coronavirus strains.
Journal ArticleDOI
ROS-mediated SRMS activation confers platinum resistance in ovarian cancer
Yunhan Jiang,Li Song,Yizhu Lin,Pawel Nowialis,Qiongmei Gao,Tao Li,Bin Li,Xiaobo Mao,Qianqian Song,Chengguo Xing,Guangrong Zheng,Shuang Huang,Lingtao Jin +12 more
Posted ContentDOI
Single molecule co-occupancy of RNA-binding proteins with an evolved RNA deaminase
TL;DR: RemORA (RNA Encoded Molecular Recording in Adenosines), a new strategy to measure RNA-binding events on single RNA molecules in cells, and genetically encodable RNA deaminase enables single-molecule identification of RNA-protein interactions with cell type specificity.
Book ChapterDOI
Full Head Performance Capture Using Multi-scale Mesh Propagation
Hanchao Li,Yizhu Lin,Xinguo Liu +2 more
TL;DR: In this paper , a template fitting based method for efficient markerless full head performance capture is presented, which starts with high-resolution multi-view videos and efficiently outputs high-fidelity full head mesh sequences with the same topology of a common template model.