Y
Yohnosuke Shimomura
Researcher at Gunma University
Publications - 40
Citations - 554
Yohnosuke Shimomura is an academic researcher from Gunma University. The author has contributed to research in topics: Diabetes mellitus & Triiodothyronine. The author has an hindex of 13, co-authored 37 publications receiving 534 citations. Previous affiliations of Yohnosuke Shimomura include Dokkyo University.
Papers
More filters
Journal ArticleDOI
Troglitazone Reduces Plasma Leptin Concentration but Increases Hunger in NIDDM Patients
Hiroyuki Shimizu,Takahumi Tsuchiya,Noriyuki Sato,Yohnosuke Shimomura,Isao Kobayashi,Masatomo Mori +5 more
TL;DR: Troglitazone significantly reduces circulating leptin levels at clinical doses and may affect the eating behavior of poorly controlled NIDDM patients through the improvement of glycemic control and/or the reduction of circulating leptin.
Journal ArticleDOI
Long-term effect of eicosapentaenoic acid ethyl (EPA-E) on albuminuria of non-insulin dependent diabetic patients
Hiroyuki Shimizu,Ken-Ichi Ohtani,Yoshito Tanaka,Noriyuki Sato,Masatomo Mori,Yohnosuke Shimomura +5 more
TL;DR: The present data indicated that EPA-E administration improved increased albumin excretion in NIDDM patients with nephropathy and its effects on albuminuria sustained for at least 12 months after the start of treatment.
Journal ArticleDOI
Mechanism of inhibitory action of ketone bodies on the production of reactive oxygen intermediates (ROIS) by polymorphonuclear leukocytes.
Noriyuki Sato,Hiroyuki Shimizu,Yohnosuke Shimomura,Kunihiko Suwa,Masatomo Mori,Isao Kobayashi +5 more
TL;DR: Evidence is provided that both 3-OHB and AcAc suppress neutrophil oxidative metabolism with respect with O2- production, and dose-dependently inhibited superoxide anion (O2-) production.
Journal ArticleDOI
Circulating concentrations of soluble leptin receptor: influence of menstrual cycle and diet therapy.
Hiroyuki Shimizu,Hiroyuki Shimizu,Kenju Shimomura,Kenju Shimomura,Mayumi Negishi,Mayumi Negishi,Miki Masunaga,Miki Masunaga,Yutaka Uehara,Yutaka Uehara,Noriyuki Sato,Noriyuki Sato,Yohnosuke Shimomura,Yohnosuke Shimomura,Kikuo Kasai,Kikuo Kasai,Masatomo Mori,Masatomo Mori +17 more
TL;DR: The results showed that serum sOB-R concentrations decrease with increasing BMI and that sex hormones likely do not affect serum s OB-R concentration in non-pregnant women, and may reflect downregulation of hypothalamic leptin receptor production as a result of an increase in circulating leptin.
Journal ArticleDOI
Changes in Ambulatory Activity and Dopamine Turnover in Streptozotocin-Induced Diabetic Rats
Yohnosuke Shimomura,Hiroyuki Shimizu,Masaki Takahashi,Noriyuki Sato,Yutaka Uehara,Kunihiko Suwa,Isao Kobayashi,Sakutaro Tadokoro,S. Kobayashi +8 more
TL;DR: The present study suggests that there are metabolic abnormalities in the striatum dopaminergic neurons of STZ-induced diabetic rats associated with decreased ambulatory activity.