Yona Avni

TL;DR: In a rat model of TAA-induced fulminant hepatic failure, melatonin improves survival and reduces liver damage and oxidative stress and it is suggested that melatonin may be utilized to reduce liver injury associated with oxidative stress.

TL;DR: Serum levels of liver enzymes, blood ammonia and prothrombin time and the stage of hepatic encephalopathy were significantly improved in rats treated with dimethylsulfoxide or dimethylthiourea compared to the other treatment groups, suggesting a role for hydroxyl radical scavenging in the protection from fulminant hepatic failure in this model.

TL;DR: Halofuginone inhibited the proliferation of other cell types of the fibrotic liver in vivo and inhibited collagen production and collagen α1(I) gene expression in the SV40‐immortalized rat HSC‐T6 cells in vitro.

TL;DR: Botox injection to the puborectalis muscle has been found to have a limited therapeutic effect on patients suffering from anismus, justifying the need for further double-blind placebo-controlled trials to determine the exact role of botulinum toxin type-A in anismu.

TL;DR: The administration of free radical scavengers prevented the development of TAA-induced liver cirrhosis probably associated with decreased oxidative stress.