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Yong Feng
Researcher at Wuhan University
Publications - 29
Citations - 1178
Yong Feng is an academic researcher from Wuhan University. The author has contributed to research in topics: Viral replication & Interferon. The author has an hindex of 11, co-authored 28 publications receiving 878 citations. Previous affiliations of Yong Feng include University of Minnesota.
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Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.
TL;DR: The RT-PCR detection of viral nucleic acid test (NAT) was one of the most quickly established laboratory diagnosis method in a novel viral pandemic, just as in this COVID-19 outbreak, and viral NAT played an important role in identifying SARS-CoV-2 infection.
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Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China.
Huan Han,Linlin Xie,Rui Liu,Jie Yang,Fang Liu,Kailang Wu,Lang Chen,Wei Hou,Yong Feng,Chengliang Zhu +9 more
TL;DR: It was found that higher concentration in venous blood of CK‐MB, MYO, ultra‐TnI, and NT‐proBNP were associated with the severity and case fatality rate of COVID‐19 and careful monitoring of the myocardiac enzyme profiles is of great importance in reducing the complications and mortality in patients with CO VID‐19.
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A comprehensive analysis of precursor microRNA cleavage by human Dicer
TL;DR: Large-scale in vitro dicing assays and mutagenesis studies showed that human Dicer cleaves most, although not all, of the 161 tested human pre-miRNAs efficiently, suggesting that Dicer interacts directly with the terminal loop region.
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Serological tests facilitate identification of asymptomatic SARS-CoV-2 infection in Wuhan, China.
TL;DR: The positive rate of COVID‐19 tests based on NAT, chest CT scan and a serological SARS‐CoV‐2 test, from April 3 to 15 in one hospital in Qingshan Destrict, Wuhan, indicates that large‐scale investigation is required to evaluate the herd immunity of the city, for the resuming people and for the re‐opened city.
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Negative feedback regulation of IL-32 production by iNOS activation in response to dsRNA or influenza virus infection
Wei Li,Fang Yang,Yan Liu,Rui Gong,Li Liu,Yong Feng,Pan Hu,Wei Sun,Qian Hao,Lei Kang,Jianguo Wu,Ying Zhu +11 more
TL;DR: It is suggested that influenza A virus infection activates IL‐32 and iNOS expression by a heretofore unrecognized complex mechanism, in which the two pro‐inflammatory factors regulate each other, involving positive and negative feedback regulatory loops.