Y
Yong-Keun Jung
Researcher at Seoul National University
Publications - 152
Citations - 19717
Yong-Keun Jung is an academic researcher from Seoul National University. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 47, co-authored 147 publications receiving 16598 citations. Previous affiliations of Yong-Keun Jung include Harvard University & Yeshiva University.
Papers
More filters
Journal ArticleDOI
Casein kinase-1γ1 and 3 Stimulate Tumor Necrosis Factor-Induced Necroptosis Through RIPK3
Song-Yi Lee,Hyun-Joo Kim,Cathena Meiling Li,Jaemin Kang,Ayaz Najafov,Muhah Jung,Soosung Kang,Shaomeng Wang,Junying Yuan,Yong-Keun Jung +9 more
TL;DR: It is shown that the decreased activity or amounts of CK1αγ1 and CK1γ3, either by treatment with a chemical inhibitor or knockdown in cells, reduced TNFα-induced necroptosis.
Journal ArticleDOI
The Nuclear Inclusion a (NIa) Protease of Turnip Mosaic Virus (TuMV) Cleaves Amyloid-β
Hye Eun Han,Saravanan Sellamuthu,Baehyun Shin,Yong Jae Lee,Sungmin Song,Ji Seon Seo,In Sun Baek,Jeomil Bae,Hannah Kim,Yung Joon Yoo,Yong-Keun Jung,Woo Keun Song,Pyung Lim Han,Woo Jin Park +13 more
TL;DR: Western blotting results showed that oligomeric as well as monomeric forms of Aβ can be degraded by NIa in vitro, indicating that the degradation of A β in the cytoplasm could be a novel strategy to control the levels of Aα, plaque formation, and the associated cell death.
Journal ArticleDOI
Aberrant role of ALK in tau proteinopathy through autophagosomal dysregulation
Jisu Park,Hyunwoo Choi,Young Doo Kim,Seohyun Kim,Youbin Kim,Youngdae Gwon,Dong Young Lee,Sung Hye Park,Won Do Heo,Yong-Keun Jung +9 more
TL;DR: In this article, an anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase, is shown to be crucial for the tau-mediated Alzheimer's disease.
Journal ArticleDOI
Characterization of subcellular localization and Ca2+ modulation of calsenilin/DREAM/KChIP3.
TL;DR: Immunohistochemical and subcellular fractionation analysis revealed that calsenilin/DREAM/KChIP3 was distributed throughout the cytoplasm of SK-N-BE2(C), Jurkat, and HeLa cells and suppressed the ATP-induced increase in intracellular Ca2+ concentrations.