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Yong-Ping Bai
Researcher at Central South University
Publications - 33
Citations - 1168
Yong-Ping Bai is an academic researcher from Central South University. The author has contributed to research in topics: Asymmetric dimethylarginine & Unfolded protein response. The author has an hindex of 16, co-authored 31 publications receiving 866 citations.
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Journal ArticleDOI
Hypoxia-elicited mesenchymal stem cell-derived exosomes facilitates cardiac repair through miR-125b-mediated prevention of cell death in myocardial infarction
Ling-Ping Zhu,Tian Tian,Jun-Yao Wang,Jing-Ni He,Tong Chen,Miao Pan,Li Xu,Huixin Zhang,Xue-Ting Qiu,Chuan-Chang Li,Kang-Kai Wang,Hong Shen,Guogang Zhang,Yong-Ping Bai +13 more
TL;DR: A new mechanism by which Hypo-Exo-derived miR125b-5p facilitates ischemic cardiac repair by ameliorating cardiomyocyte apoptosis is illustrated, and the IMT- Exo may serve as a novel drug carrier that enhances the specificity of drug delivery for isChemic disease.
Journal ArticleDOI
Ceramide is upregulated and associated with mortality in patients with chronic heart failure.
Jingjia Yu,Wei Pan,Ruizheng Shi,Tianlun Yang,Yuan-Jian Li,Guolong Yu,Yong-Ping Bai,Edward H. Schuchman,Xingxuan He,Guogang Zhang +9 more
TL;DR: Plasma ceramide levels were increased and correlated with the severity of CHF, and were an independent risk factor of mortality in patients with CHF and reduced left ventricular systolic function.
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Ox-LDL induces endothelial cell apoptosis via the LOX-1-dependent endoplasmic reticulum stress pathway.
TL;DR: LOX-1 plays a critical role in ox-LDL-induced endothelial cell apoptosis via the ER stress pathway and is attenuated by Nox-4 siRNA attenuated the up-regulated expression of GRP78, PERK, IRE1, and XBP-1 to reduce ox- LDL- induced endothelial Cell apoptosis.
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Involvement of vascular peroxidase 1 in angiotensin II-induced vascular smooth muscle cell proliferation
Ruizheng Shi,Chang-Ping Hu,Qiong Yuan,Tianlun Yang,Jun Peng,Yuan-Jian Li,Yong-Ping Bai,Zehong Cao,Guangjie Cheng,Guogang Zhang +9 more
TL;DR: VPO1 is a novel regulator of vascular smooth muscle cell proliferation via NADPH oxidase-H(2)O(2)-VPO1-hypochlorous acid-ERK1/2 pathways, which may contribute to vascular remodelling in hypertension.
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Elevation of ceramide and activation of secretory acid sphingomyelinase in patients with acute coronary syndromes.
Wei Pan,Jingjia Yu,Ruizheng Shi,Lei Yan,Tianlun Yang,Yuan-Jian Li,Zhuohua Zhang,Guolong Yu,Yong-Ping Bai,Edward H. Schuchman,Xingxuan He,Guogang Zhang +11 more
TL;DR: Serial changes in plasma ceramide and S-SMase activity were documented in patients with ACS and provide an insight into the molecular mechanism of plaque destabilization.