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Yongming Xie
Researcher at University of California, Los Angeles
Publications - 26
Citations - 3226
Yongming Xie is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Mass spectrometry & Proteome. The author has an hindex of 19, co-authored 26 publications receiving 2998 citations. Previous affiliations of Yongming Xie include University of Southern California.
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Journal ArticleDOI
The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions
Paul C. Denny,Fred K. Hagen,Markus Hardt,Lujian Liao,Weihong Yan,Martha Arellanno,Sara Bassilian,Gurrinder S. Bedi,Pinmannee Boontheung,Daniel Cociorva,Claire M. Delahunty,Trish Denny,Jason Dunsmore,Kym F. Faull,Joyce Gilligan,Mireya Gonzalez-Begne,Frédéric Halgand,Steven C. Hall,Xuemei Han,Bradley S. Henson,Johannes Hewel,Shen Hu,Sherry Jeffrey,Jiang Jiang,Joseph A. Loo,Rachel R. Ogorzalek Loo,Daniel Malamud,James E. Melvin,Olga Miroshnychenko,Mahvash Navazesh,Richard K. Niles,Sung Kyu Park,Akraporn Prakobphol,Prasanna Ramachandran,Megan Richert,Sarah Robinson,Melissa Sondej,Puneet Souda,Mark A. Sullivan,Jona Takashima,Shawn Than,Jianghua Wang,Julian P. Whitelegge,H. Ewa Witkowska,Lawrence E. Wolinsky,Yongming Xie,Tao Xu,Weixia Yu,Jimmy Ytterberg,David T.W. Wong,John R. Yates,Susan J. Fisher +51 more
TL;DR: A catalogue of the salivary proteome of healthy individuals allows future analyses ofSaliva samples from individuals with oral and systemic diseases, with the goal of identifying biomarkers with diagnostic and/or prognostic value for these conditions; another possibility is the discovery of therapeutic targets.
Journal ArticleDOI
Salivary proteomic and genomic biomarkers for primary sjögren's syndrome
Shen Hu,Jianghua Wang,Jiska Meijer,Sonya Ieong,Yongming Xie,Tianwei Yu,Hui Zhou,Sharon Henry,Arjan Vissink,J. Pijpe,Cees G. M. Kallenberg,David Elashoff,Joseph A. Loo,David T.W. Wong +13 more
TL;DR: It is found that WS contains more informative proteins, peptides, and mRNA, as compared with gland-specific saliva, that can be used in generating candidate biomarkers for the detection of primary SS.
Journal ArticleDOI
Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry.
Shen Hu,Yongming Xie,Prasanna Ramachandran,Rachel R. Ogorzalek Loo,Yang Li,Joseph A. Loo,David T.W. Wong +6 more
TL;DR: Large‐scale identification of salivary proteins was demonstrated by using shotgun proteomics and two‐dimensinal gel electrophoresis‐mass spectrometry (2‐DE‐MS) to cataloged 309 proteins from human whole saliva.
Journal ArticleDOI
Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins
Eugenia Leikina,Hélène Delanoë-Ayari,Kamran Melikov,Myoung-Soon Cho,Andrew Y. Chen,Alan J. Waring,Wei Wang,Yongming Xie,Joseph A. Loo,Robert I. Lehrer,Leonid V. Chernomordik +10 more
TL;DR: It is shown that the θ-defensin retrocyclin 2 (RC2) inhibited influenza virus infection by blocking membrane fusion mediated by the viral hemagglutinin.
Journal ArticleDOI
Identification of N-Linked Glycoproteins in Human Saliva by Glycoprotein Capture and Mass Spectrometry
Prasanna Ramachandran,Pinmannee Boontheung,Yongming Xie,Melissa Sondej,David T.W. Wong,Joseph A. Loo +5 more
TL;DR: Using the hydrazide coupling and release method, 84 formerly N-glycosylated peptides from 45 unique N- glycoproteins were identified, including 44 new sites of N-linked glycosylation on the proteins.