Yosef S. Haviv

TL;DR: Inhibition of TGF-β function promoted lymphatic regeneration, decreased tissue fibrosis, decreased chronic inflammation and Th2 cell migration, and improved lymphatic function, and the use of these strategies may represent a novel means of preventing lymphedema after lymph node resection.

TL;DR: There is no advantage of dopamine over adequate hydration in patients with mild to moderate renal failure or DM undergoing coronary angiography, and Dopamine should be avoided in Patients with PVD exposed to contrast medium.

TL;DR: Data indicate that the survivin promoter is a promising tumor-specific promoter for transcriptional targeting of adenovirus-based vectors and CRAds for malignant gliomas, and the strategy of using survivin-CRAds may translate into an experimental therapeutic approach that can be used in human clinical trials.

TL;DR: Whether adipose-derived stem cells can be used in lymphatic tissue-engineering by altering the balance between pro- and anti-lymphangiogenic cytokines is determined and short-term stimulation of ASCs with VEGF-C results in increased expression of V EGF-A, VEGf-C and Prox-1 in vitro and is associated with a marked increase lymphangiogenesis response after in vivo implantation.

TL;DR: Novel approaches for conditional gene expression in cancer cells are discussed and the regulation of both replication and transgene expression by conditionally-replicative viruses are discussed to increase the therapeutic index of future vectors for cancer gene therapy.