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Yossombat Changtrakul
Researcher at Khon Kaen University
Publications - 8
Citations - 210
Yossombat Changtrakul is an academic researcher from Khon Kaen University. The author has contributed to research in topics: Thalassemia & Hemoglobin. The author has an hindex of 6, co-authored 7 publications receiving 197 citations.
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Journal ArticleDOI
A reliable screening protocol for thalassemia and hemoglobinopathies in pregnancy: an alternative approach to electronic blood cell counting.
Kanokwan Sanchaisuriya,Supan Fucharoen,Goonnapa Fucharoen,Thawalwong Ratanasiri,Pattara Sanchaisuriya,Yossombat Changtrakul,Uthai Ukosanakarn,Wichai Ussawaphark,Frank P. Schelp +8 more
TL;DR: A combination of modified osmotic fragility (OF) and DCIP tests should prove useful and applicable to prenatal screening programs for thalassemia and hemoglobinopathies in communities with limited facilities and economic resources.
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Molecular and hematological profiles of hemoglobin EE disease with different forms of α-thalassemia
Goonnapa Fucharoen,Jaruwan Trithipsombat,Suparerk Sirithawee,Supawadee Yamsri,Yossombat Changtrakul,Kanokwan Sanchaisuriya,Supan Fucharoen +6 more
TL;DR: Overlapping levels of Hb E, Hb F, and other hematological parameters were observed which did not predict clinical severity, indicating a need for α-globin gene analysis for accurate diagnosis and improved genetic counseling.
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Thalassemia and hemoglobinopathies in Southeast Asian newborns: diagnostic assessment using capillary electrophoresis system
Hataichanok Srivorakun,Goonnapa Fucharoen,Yossombat Changtrakul,Patcharee Komwilaisak,Supan Fucharoen +4 more
TL;DR: The capillary electrophoresis system is applicable to newborn screening for common forms of thalassemia in Southeast Asia and could provide useful data for presumptive diagnoses of cases, especially those with Hb E and α-thalassemia.
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Association of Hb Thailand [α56(E5)Lys→Thr] and Hb Phnom Penh [α117(GH5)-Ile-α118(H1)] with α(0)-thalassemia: molecular and hematological features and differential diagnosis.
Kritsada Singha,Hataichanok Srivorakun,Goonnapa Fucharoen,Yossombat Changtrakul,Patcharee Komwilaisak,Arunee Jetsrisuparb,Rawiwan Puangplruk,Supan Fucharoen +7 more
TL;DR: The molecular and hematological characteristics of two rare hemoglobin (Hb) variants found in associations with a common α0-thalassemia in Thai patients are reported and could be confirmed by polymerase chain restriction-restriction fragment length polymorphism (PCR-RFLP) and allele-specific PCR assays.
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Effective screening for double heterozygosity of Hb E/α0-thalassemia
Kanokwan Sanchaisuriya,Sunisa Chirakul,Hataichanok Srivorakun,Goonnapa Fucharoen,Supan Fucharoen,Yossombat Changtrakul,Pattara Sanchaisuriya +6 more
TL;DR: It is concluded that Hb E level’s< 26%, MCV <74 fl, and MCH’<“ 24 pg could be used for screening αo-thalassemia in heterozygous H b E, however, to improve specificity and PPV of the tests, a combination of HB E level with either MCV or MCH cutoff points is recommended.