Y
Young Do Jung
Researcher at Chonnam National University
Publications - 130
Citations - 5716
Young Do Jung is an academic researcher from Chonnam National University. The author has contributed to research in topics: Angiogenesis & Signal transduction. The author has an hindex of 39, co-authored 119 publications receiving 5256 citations. Previous affiliations of Young Do Jung include University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells.
Young Do Jung,Young Do Jung,M. S. Kim,Boo A. Shin,Kee Oh Chay,Bong Whan Ahn,Wenbiao Liu,Corazon D. Bucana,Gary E. Gallick,Lee M. Ellis +9 more
TL;DR: Green tea catechins may exert at least part of its anticancer effect by inhibiting angiogenesis through blocking the induction of VEGF.
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Effects of combination anti-vascular endothelial growth factor receptor and anti-epidermal growth factor receptor therapies on the growth of gastric cancer in a nude mouse model.
Young Do Jung,Paul F. Mansfield,Morihisa Akagi,Akihiko Takeda,Wenbiao Liu,Corazon D. Bucana,Daniel J. Hicklin,Lee M. Ellis +7 more
TL;DR: The combination of anti-VEGF-R and anti-EGF-R therapies was effective in inhibiting gastric cancer growth and support the hypothesis that inhibiting multiple biological pathways that mediate tumour growth may be an effective therapeutic strategy.
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Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors
Raymond M. Shaheen,Syed A. Ahmad,Wenbiao Liu,Niels Reinmuth,Young Do Jung,William W. Tseng,Kenneth E. Drazan,Corazon D. Bucana,Daniel J. Hicklin,Lee M. Ellis +9 more
TL;DR: It is suggested that DC101 inhibits angiogenesis, endothelial cell survival, and VEGF-mediated ascites formation in a murine model of colon cancer carcinomatosis, and combination anti-VEGF and anti-EGFR therapy may represent a novel therapeutic strategy for the management of colon peritoneal carcinom atosis.
Journal ArticleDOI
Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea
Young Do Jung,Lee M. Ellis +1 more
TL;DR: Understanding the basic principles by which EGCG inhibits tumour invasion and angiogenesis may lead to the development of new therapeutic strategies, in addition to supporting the role of green tea as a cancer chemopreventive agent.
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Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival.
Niels Reinmuth,Wenbiao Liu,Young Do Jung,Syed A. Ahmad,Raymond M. Shaheen,Fan Fan,Corazon D. Bucana,Gerald McMahon,Gary E. Gallick,Lee M. Ellis +9 more
TL;DR: It is hypothesized that PDGF (platelet‐derived growth factor)‐BB, a cytokine released from tumor and ECs, mediates pericyte function by inducing VEGF, which in turn may affect EC survival.