Young Il Yang

TL;DR: A critical role of IRF‐1 is found in the regulation of constitutive and IFN‐γ‐induced expression of B7‐H1 in cancer cells, and AG490, a Janus activated kinase/signal transducer and activator of transcription inhibitor, greatly abolished the responsiveness of A549 cells to IFN-γ by reducing the IRF•1 transcription.

TL;DR: This study shows that application of DBPs reduces the fibrous tissue encapsulation and foreign body giant cell response that commonly occurs at the interface of PLGA.

TL;DR: An epicardial delivery system of vascular endothelial growth factor (VEGF) and cardiac stem cells (CSCs) using poly(l-lactic acid) (PLLA) mat applied to the acutely infarcted myocardium showed meaningful therapeutic effects on angiogenesis and cardiomyogenesis, leading to reduced cardiac remodeling and enhanced global cardiac function.

TL;DR: Not only DNA quantity measurement of the cells but also the number of cells within the cross-sectional area of the scaffold was investigated, and various pore size specimens tended to degrade more and faster than uniform-pore size specimen in PBS solution.

TL;DR: The results indicate that the porous PLGA membranes containing beta-glucan interacted favorably with the membrane and the topical administration of beta- glucan was useful in promoting wound healing.