Y
Youngbin Kwak
Researcher at University of Massachusetts Amherst
Publications - 36
Citations - 2362
Youngbin Kwak is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Parkinson's disease & Resting state fMRI. The author has an hindex of 16, co-authored 32 publications receiving 1983 citations. Previous affiliations of Youngbin Kwak include University of Michigan & Duke University.
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Journal ArticleDOI
Motor Control and Aging: Links to Age-Related Brain Structural, Functional, and Biochemical Effects
Rachael D. Seidler,Jessica A. Bernard,Taritonye B. Burutolu,Brett W. Fling,Mark T. Gordon,Joseph T. Gwin,Youngbin Kwak,David B. Lipps +7 more
TL;DR: In general, older adults exhibit involvement of more widespread brain regions for motor control than young adults, particularly the prefrontal cortex and basal ganglia networks, resulting in an imbalance of "supply and demand".
Journal ArticleDOI
Altered Resting State Cortico-Striatal Connectivity in Mild to Moderate Stage Parkinson's Disease
Youngbin Kwak,Scott Peltier,Nicolaas I. Bohnen,Martijn L.T.M. Müller,Praveen Dayalu,Rachael D. Seidler +5 more
TL;DR: PD and l-DOPA modulate striatal resting state BOLD signal oscillations and cortico-striatal network coherence and these effects are evaluated using resting state functional connectivity MRI in mild to moderate stage Parkinson's patients on and off l- DOPA and age-matched controls.
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Dopamine overdose hypothesis: Evidence and clinical implications
TL;DR: This review considers the evidence that has accumulated in the areas of reversal learning, motor sequence learning, and other cognitive tasks and considers the purported inverted‐U shaped relationship between dopamine levels and performance.
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Disrupted cortico-cerebellar connectivity in older adults.
Jessica A. Bernard,Scott Peltier,Jillian Lee Wiggins,Susanne M. Jaeggi,Martin Buschkuehl,Martin Buschkuehl,Brett W. Fling,Youngbin Kwak,Youngbin Kwak,John Jonides,Christopher S. Monk,Rachael D. Seidler +11 more
TL;DR: Understanding of the resting state networks of the aging brain to include cortico-cerebellar networks is extended, and associations between connectivity strength and both sensorimotor and cognitive task performances indicate that age differences in network connectivity strength are important for behavior.
Journal ArticleDOI
Effect of dopaminergic medications on the time course of explicit motor sequence learning in Parkinson's disease.
TL;DR: It is demonstrated that dopaminergic medications may selectively impair early-phase motor sequence learning, and the dopamine overdose effects previously reported for (antero)ventral striatum-mediated cognitive tasks to motor sequencelearning are extended and generalized.