Youngmin Bu

TL;DR: Investigation of whether CGA has protective effects against cerebral ischemia and whether these effects are due to modification of brain edema-related vascular factors suggests that CGA reduces brain damage, BBB damage andbrain edema by radical scavenging activity and the inhibitory effects on MMP-2 and MMP9.

TL;DR: In vivo findings were confirmed by in vitro data illustrating that hDPSCs showed superior neuroprotective, migratory, and in vitro angiogenic effects in oxygen–glucose deprivation-injured human astrocytes (hAs) versus hBM-MSCs.

TL;DR: The current results support the clinical usage of SSE in the East Asian region treating atherothrombotic diseases and may represent a new natural source to develop antiplatelet agents.

TL;DR: Sesame seeds and its antioxidants may be a potent natural agent with both therapeutic applications and use in preventing human illness such as neurodegenerative disease.

TL;DR: It is found that various in vitro and in vivo models of traumatic brain injury markedly enhanced LRRK2 expression in neurons and also increased the level of hypoxia-inducible factor (HIF)-1α, and application of G1023 substantially prevented brain tissue damage, cell death, and inflammatory response and alleviated motor and cognitive defects induced by controlled cortical impact injury.