Y
Yu Xu
Researcher at Nanjing Medical University
Publications - 8
Citations - 84
Yu Xu is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Vasodilation & Nitric oxide. The author has an hindex of 4, co-authored 6 publications receiving 42 citations.
Papers
More filters
Journal ArticleDOI
Angiotensin-(1-7) induced vascular relaxation in spontaneously hypertensive rats.
Feng Zhang,Haiyang Tang,Shuo Sun,Yuru Luo,Xing-Sheng Ren,Ai-Dong Chen,Yu Xu,Peng Li,Ying Han +8 more
TL;DR: Activation of the Mas receptor by Ang-(1-7) relaxes the MA, CA, and PA through the NO-cGMP-PKG pathway, which contributes to the decrease of arterial pressure in SHR.
Journal ArticleDOI
Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats.
Feng Zhang,Yu Xu,Yan Pan,Shuo Sun,Ai-Dong Chen,Peng Li,Changlei Bao,Jian Wang,Haiyang Tang,Haiyang Tang,Ying Han +10 more
TL;DR: Investigation of the influence of angiotensin- (Ang-) (1-7) and Ang II on blood pressure and ACh-induced vascular relaxation, as well as their interactive roles and downstream signal pathways in SHR and WKY indicate that the activation of the Mas receptor by Ang-(1- 7) can improve endothelial function and decrease MAP inSHR and inhibit the deteriorative effect of Ang II
Journal ArticleDOI
Salusin-β Promotes Vascular Calcification via Nicotinamide Adenine Dinucleotide Phosphate/Reactive Oxygen Species-Mediated Klotho Downregulation.
Hai-Jian Sun,Feng Zhang,Yu Xu,Shuo Sun,Hui-Ping Wang,Qiong Du,Chenxin Gu,Stephen M. Black,Ying Han,Haiyang Tang,Haiyang Tang +10 more
TL;DR: Vascular calcification is a hallmark feature of cardiovascular disease and a significant risk factor for morbidity and mortality and Salusin-β exerts cardiovascular regulating effe...
Journal ArticleDOI
A TOR2A Gene Product: Salusin-β Contributes to Attenuated Vasodilatation of Spontaneously Hypertensive Rats
TL;DR: Results indicated that enhanced salusin-β activity is involved in attenuated endothelium-dependent vasodilatation pathogenesis in SHR by activating NAD(P)H oxidase derived ROS generation and inhibiting eNOS activation and NO release.
Journal ArticleDOI
Research Progress on Pulmonary Arterial Hypertension and the Role of the Angiotensin Converting Enzyme 2-Angiotensin-(1–7)-Mas Axis in Pulmonary Arterial Hypertension
Feng Zhang,Aidong Chen,Yan Pan,Xingxing Wang,Yu Xu,Ankit A. Desai,Haiyang Tang,Haiyang Tang,Ying Han +8 more
TL;DR: In this paper, the ACE2-Ang-(1-7)-Mas axis was proposed as a novel target for the treatment of pulmonary arterial hypertension (PAH) based on established functions.