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Yu-Zhou Chang
Researcher at Capital Medical University
Publications - 11
Citations - 299
Yu-Zhou Chang is an academic researcher from Capital Medical University. The author has contributed to research in topics: Glioma & Temozolomide. The author has an hindex of 6, co-authored 10 publications receiving 104 citations.
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Journal ArticleDOI
YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma.
Rui-Chao Chai,Yu-Zhou Chang,Xin Chang,Bo Pang,Song Yuan An,Kenan Zhang,Yuanhao Chang,Tao Jiang,Yongzhi Wang +8 more
TL;DR: In this paper, the role and mechanism of the RNA N6,2′-O-dimethyladenosine (m6A) reader, YTH N6-methyladenosines RNA binding protein 2 (YTHDF2), in regulating the malignant progression of gliomas was investigated.
Journal ArticleDOI
METTL3 enhances the stability of MALAT1 with the assistance of HuR via m6A modification and activates NF-κB to promote the malignant progression of IDH-wildtype glioma.
Yu-Zhou Chang,Rui-Chao Chai,Bo Pang,Xin Chang,Song Yuan An,Kenan Zhang,Tao Jiang,Yongzhi Wang +7 more
TL;DR: Zhang et al. as discussed by the authors investigated the role and mechanism of the m6A writer METTL3 in regulating the malignant progression of IDH-wildtype gliomas.
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The molecular characteristics of spinal cord gliomas with or without H3 K27M mutation
Rui-Chao Chai,Yao-Wu Zhang,Yu-Qing Liu,Yu-Zhou Chang,Bo Pang,Tao Jiang,Wen-Qing Jia,Yong-Zhi Wang +7 more
TL;DR: Findings indicate that spinal cord astrocytomas are considerably different from hemispheric and brainstem astroCytomas in terms of their molecular profiles, and that the histological grade cannot be ignored when assessing the prognosis of H3 K27M-mutant spinal cordAstrocytic tumors.
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Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma
Rui-Chao Chai,Kenan Zhang,Yu-Zhou Chang,Fan Wu,Yu-Qing Liu,Zheng Zhao,Kuanyu Wang,Yuanhao Chang,Tao Jiang,Yongzhi Wang +9 more
TL;DR: A 25-1p19q-gene signature has powerfully predictive value for both malignant molecular pathological features and prognosis across distinct subgroups of 1p/19q non-codel gliomas.
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Predictive value of MGMT promoter methylation on the survival of TMZ treated IDH -mutant glioblastoma.
Rui-Chao Chai,Guanzhang Li,Yu-Qing Liu,Kenan Zhang,Zheng Zhao,Fan Wu,Yu-Zhou Chang,Bo Pang,Jing-Jun Li,Yang-Fang Li,Tao Jiang,Yongzhi Wang +11 more
TL;DR: In this paper, the role of MGMT promoter methylation in IDH-mutant glioblastoma was investigated and shown to be correlated with longer OS in GBM patients.