Y
Yuan Chang
Researcher at University of Pittsburgh
Publications - 204
Citations - 39010
Yuan Chang is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Kaposi's sarcoma-associated herpesvirus & Merkel cell polyomavirus. The author has an hindex of 74, co-authored 177 publications receiving 37240 citations. Previous affiliations of Yuan Chang include Santa Clara Valley Medical Center & Northwestern University.
Papers
More filters
Journal ArticleDOI
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
Yuan Chang,Ethel Cesarman,Melissa S. Pessin,Frank Lee,Janice Culpepper,Daniel M. Knowles,Patrick S. Moore +6 more
TL;DR: unique sequences present in more than 90 percent of Kaposi's sarcoma tissues obtained from patients with acquired immunodeficiency syndrome (AIDS) appear to define a new human herpesvirus.
Journal ArticleDOI
Helicobacter pylori infection and the risk of gastric carcinoma.
Julie Parsonnet,Gary D. Friedman,Daniel P. Vandersteen,Yuan Chang,Joseph H. Vogelman,Norman Orentreich,Richard K. Sibley +6 more
TL;DR: Infection with H. pylori is associated with an increased risk of gastric adenocarcinoma and may be a cofactor in the pathogenesis of this malignant condition.
Journal ArticleDOI
Kaposi's Sarcoma–Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity–Based Lymphomas
TL;DR: A high degree of conservation of KSHV sequences in Kaposi's sarcoma and in the eight lymphomas suggests the presence of the same agent in both lesions, suggesting that a novel herpesvirus has a pathogenic role in AIDS-related body-cavity-based lymphomas.
Journal ArticleDOI
Clonal integration of a polyomavirus in human Merkel cell carcinoma.
TL;DR: In six of eight MCV-positive MCCs, viral DNA was integrated within the tumor genome in a clonal pattern, suggesting that MCV infection and integration preceded clonal expansion of the tumor cells, and MCV may be a contributing factor in the pathogenesis of MCC.
Journal ArticleDOI
Nucleotide sequence of the kaposi sarcoma-associated herpesvirus (hhv8)
James J. Russo,Roy A. Bohenzky,Minchen Chien,Chen J,Yan M,Maddalena D,John Preston Parry,Peruzzi D,Isidore S. Edelman,Yuan Chang,Patrick S. Moore +10 more
TL;DR: Terminal repeat analysis of virus DNA from a KS lesion suggests a monoclonal expansion of KSHV in the KS tumor.