Y
Yuan Ching Chang
Researcher at Mackay Memorial Hospital
Publications - 5
Citations - 293
Yuan Ching Chang is an academic researcher from Mackay Memorial Hospital. The author has contributed to research in topics: Xanthine oxidase & Apoptosis. The author has an hindex of 3, co-authored 5 publications receiving 260 citations. Previous affiliations of Yuan Ching Chang include Mackay Medical College.
Papers
More filters
Journal ArticleDOI
Structure-activity relationship of coumarin derivatives on xanthine oxidase-inhibiting and free radical-scavenging activities
Hsiu Chen Lin,Shin Hui Tsai,Chien Shu Chen,Yuan Ching Chang,Yuan Ching Chang,Chi Ming Lee,Zhi Yang Lai,Zhi Yang Lai,Chun Mao Lin +8 more
TL;DR: The hypoxanthine/XO reaction in the DMPO-ESR technique was used to assess the combined effect on enzyme inhibition and ROS suppression by these coumarins, and the results showed that esculetin was the most potent agent among the tested compounds.
Journal ArticleDOI
Isovitexin suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages.
Chun Mao Lin,Sheng-Tung Huang,Yu Chih Liang,Mei Shan Lin,Chwen Ming Shih,Yuan Ching Chang,Yuan Ching Chang,Tzong-Yueh Chen,Chien Tsu Chen +8 more
TL;DR: The results suggest that isovitexin, a food phytochemical contained in dietary rice products, might have biological significance.
Journal ArticleDOI
Structure-activity relationship of C6-C3 phenylpropanoids on xanthine oxidase-inhibiting and free radical-scavenging activities.
Yuan Ching Chang,Fu Wei Lee,Chien Shu Chen,Sheng-Tung Huang,Shin Hui Tsai,Shih Hao Huang,Chun Mao Lin +6 more
TL;DR: In this article, the effects of the derivatives on the inhibition of xanthine oxidase (XO) activity, and the structure-activity relationships (SARs) of these derivatives against XO activity were further examined using computer-aided molecular modeling.
Journal ArticleDOI
Study on Dissolution Profile of Commercial Glyburide Tablets
Journal ArticleDOI
Down-regulation of fatty acid synthase is associated with decreased Akt activation in lovastatin induced apoptosis cells
Yuan Ching Chang,Yuan Ching Chang,Yen Hua Huang,Chwen Ming Shih,Jui Yu Wu,Chien Liang Liu,Chien Liang Liu,Shwu Huey Wang,Chun Mao Lin +8 more
TL;DR: Results implicate that lovastatin inhibiting FAS expression is associated with the decreased Akt activation, and reverse transcription PCR analysis showed that Lovastatin upregulated PPAR-γ and inhibited SREBP-1 mRNA expression in HepG2 cells.