Yuan Mei

TL;DR: It is shown that re-expression of the Shank3 gene in adult mice led to improvements in synaptic protein composition, spine density and neural function in the striatum, and a certain degree of continued plasticity in the adult diseased brain is demonstrated.

TL;DR: The findings demonstrate, for the first time, an important role for nArgBP2 in neuronal dendritic development and excitatory synaptic transmission, which may inform exploration of neurobiological basis of SORBS2 deficiency in intellectual disability.

TL;DR: In this article , the effects of capsaicin and fermentation time on the microbial community and flavor compounds of chili paste were investigated, and it was shown that after capsaicins supplementation, the total acid was significantly decreased along with lower total bacteria, especially lactic acid bacteria.

TL;DR: This article investigated the developmental requirement of Shank3 in mice, a prominent monogenic autism gene that is estimated to contribute to approximately 1% of all autism spectrum disorder cases, and showed that re-expression of the Shank3 gene in adult mice led to improvements in synaptic protein composition, spine density and neural function in the striatum.