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Yuanlong Li
Researcher at Zhengzhou University
Publications - 9
Citations - 136
Yuanlong Li is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 3, co-authored 4 publications receiving 56 citations.
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Journal ArticleDOI
Long Non-coding RNA MALAT1 Inhibits Neuron Apoptosis and Neuroinflammation While Stimulates Neurite Outgrowth and Its Correlation With MiR-125b Mediates PTGS2, CDK5 and FOXQ1 in Alzheimer's Disease.
TL;DR: Lnc-MALAT1 might be interacted with miR-125b to inhibit neuron apoptosis and inflammation while promote neurite outgrowth in AD.
Journal ArticleDOI
Circular RNA expression profile of Alzheimer’s disease and its clinical significance as biomarkers for the disease risk and progression
Yuanlong Li,Hua Fan,Jun Sun,Ming Ni,Lei Zhang,Ci Chen,Xuejiao Hong,Fengqin Fang,Wei Zhang,Peizhi Ma,Peizhi Ma +10 more
TL;DR: This study provides an overview of circRNA expression profile in AD, and identifies that circ-AXL, circ-GPHN and circ-PCCA hold clinical implications for guiding disease management in AD patients.
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Cytochrome P450 3A4-Mediated Bioactivation and Its Role in Nomilin-Induced Hepatotoxicity
TL;DR: Evidence is provided that CYP3A4-mediated bioactivation was indispensable in nomilin induced hepatotoxicity and tetrahydro-nomilin was found to be non-hepatotoxic.
Journal ArticleDOI
Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer
Mingjie An,Jian Huang,Yansi Lin,Yuming Luo,Yao Kong,Mingrui Pang,Dingwen Zhang,Jiabin Yang,Jiancheng Chen,Yuanlong Li,Changhao Chen,Tianxin Lin +11 more
TL;DR: SUMOylation-induced nuclear export of circNCOR1 is highlighted as a key event regulating TGFβ-SMAD signaling and BCa lymphangiogenesis, thus supporting circNCor1 as a novel therapeutic agent for patients with LN metastatic BCa.
Journal ArticleDOI
Circular RNA AXL increases neuron injury and inflammation through targeting microRNA-328 mediated BACE1 in Alzheimer’s disease
Yuanlong Li,Xiong Han,Hua Fan,Jun Sun,Ming Ni,Lulu Zhang,Fengqin Fang,Wei Hong Zhang,Peizhi Ma +8 more
TL;DR: In this article , the effect of circ-AXL on regulating neuron injury and inflammation in cellular AD models and its underlying molecular mechanism was investigated, and it was shown that circ-axl may serve as a potential treatment target via miR-328 mediated BACE1 in AD.