Yue Ju

TL;DR: This is the first report to show that PS ionization is a promising ionization method for nonconvalent protein complexes and it is possible to detect hemoglobin tetramer from a blood sample with minimal sample preparation.

TL;DR: It is demonstrated that dissociation of protein complexes by surface collisions, at the lower end of the typical surface-induced dissociation (SID) collision energy range, consistently cleaves the weakest protein:protein interfaces, producing products that are reflective of the known structure.

TL;DR: The suitability of SID to locate the ligand binding sites in protein complexes to study C-reactive protein pentamer and cholera toxin B has potential application in localizing sites of small ligandbinding for multisubunit protein-ligand complexes.

TL;DR: In this article, the authors used biochemical and mass spectrometry approaches to determine the disulfide linkages present in the recombinant Phα1β peptide, which has been shown to have an extensive analgesic effect with fewer side effects than ω-conotoxin MVIIA.

TL;DR: It is demonstrated that the primary AmrZ form in solution is tetrameric, and the C-terminal domain is essential for efficient AmRZ-mediated activation and repression of its targets.