Yueyu Bai

TL;DR: The role of circLMO7—one of the most down-regulated circRNAs when comparing adult to embryonic muscle tissue—in bovine muscle development is characterized and novel insights into the regulatory mechanisms underlying skeletal muscle development are provided.

TL;DR: Ribo-Zero RNA-Seq data provide a valuable genomic resource for the identification of lncRNAs with functional roles in adipocyte differentiation but also reveal new insights into understanding the mechanisms of adipogenic differentiation.

TL;DR: Results demonstrated that circFGFR4 binding miR-107 promotes cell differentiation via targeting Wnt3a in bovine primary myoblasts.

TL;DR: It is demonstrated that circFUT10 was highly (but differentially) expressed in embryonic and adult skeletal muscle tissue and regulated myoblasts differentiation and cell survival by directly binding to miR‐133a and inhibiting miR-133a activity.

TL;DR: The first analysis of lncRNA landscape in bovine embryonic, neonatal and adult skeletal muscle using Ribo-Zero RNA-Seq is reported, showing that lncMD acts as a ceRNA to sequester miR-125b, leading to heightened IGF2 expression and thus promotes muscle differentiation.