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Yuhua Shang
Researcher at Brandeis University
Publications - 4
Citations - 636
Yuhua Shang is an academic researcher from Brandeis University. The author has contributed to research in topics: Sleep deprivation & Sleep induction. The author has an hindex of 4, co-authored 4 publications receiving 578 citations. Previous affiliations of Yuhua Shang include Howard Hughes Medical Institute.
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Journal ArticleDOI
PDF Cells Are a GABA-Responsive Wake-Promoting Component of the Drosophila Sleep Circuit
Katherine M. Parisky,Jose Agosto,Jose Agosto,Stefan R. Pulver,Yuhua Shang,Yuhua Shang,Elena A. Kuklin,James J L Hodge,KyeongJin Kang,Xu Liu,Paul A. Garrity,Michael Rosbash,Michael Rosbash,Leslie C. Griffith +13 more
TL;DR: These features of the Drosophila sleep circuit, GABAergic control of onset and maintenance as well as peptidergic control of arousal, support the idea that features of sleep-circuit architecture aswell as the mechanisms governing the behavioral transitions between sleep and wake are conserved between mammals and insects.
Journal ArticleDOI
Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila
Elzbieta Kula-Eversole,Emi Nagoshi,Emi Nagoshi,Yuhua Shang,Joseph Rodriguez,Ravi Allada,Michael Rosbash +6 more
TL;DR: The results suggest that RNA cycling is much more prominent in circadian neurons than elsewhere in heads and may be particularly important for the functioning of these neurons.
Journal ArticleDOI
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
Yuhua Shang,Nathan C. Donelson,Christopher G. Vecsey,Fang Guo,Fang Guo,Michael Rosbash,Michael Rosbash,Leslie C. Griffith +7 more
TL;DR: The profound effect of sNPF on sleep indicates that it is an important sleep-promoting molecule.
Short neuropeptide F is a sleep-promoting inhibitory modulator
Yuhua Shang,Nathan C. Donelson,Christopher G. Vecsey,Fang Guo,Fang Guo,Michael Rosbash,Michael Rosbash,Leslie C. Griffith +7 more
TL;DR: In this article, the authors screened for sleep-promoting cells and identified neurons expressing neuropeptide Y-like short neuropeptic F (sNPF) and found that only a subset of sNPF-expressing neurons, which includes the small ventrolateral clock neurons, is sleep promoting.