Katherine M. Parisky

TL;DR: These features of the Drosophila sleep circuit, GABAergic control of onset and maintenance as well as peptidergic control of arousal, support the idea that features of sleep-circuit architecture aswell as the mechanisms governing the behavioral transitions between sleep and wake are conserved between mammals and insects.

TL;DR: It is shown that sleep is regulated by GABA in Drosophila and that a mutant GABAA receptor, RdlA302S, specifically decreases sleep latency, and this results suggest that this biophysical property of the channel, specifically channel desensitization, underlies the regulation of sleep latency in flies.

TL;DR: In this paper, the effect of temperature on sleep in Drosophila has been investigated and it has been shown that increased ambient temperature reorganizes sleep patterns in a way similar to the human response to heat, increasing daytime sleep while decreasing nighttime sleep.

TL;DR: A null mutant for dArc1 is generated and it is shown that this gene is not involved in synaptic plasticity at the larval neuromuscular junction or in formation or decay of short-term memory of courtship conditioning, but rather is a modifier of stress-induced behavior.

TL;DR: The effect of temperature on sleep reflects coordinated regulation by light, the homeostat, and components of the clock, allowing animals to reorganize sleep patterns in response to high temperature with rough preservation of the total amount of sleep.