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Yuhui Zhao

Researcher at Capital Medical University

Publications -  8
Citations -  116

Yuhui Zhao is an academic researcher from Capital Medical University. The author has contributed to research in topics: Repolarization & Messenger RNA. The author has an hindex of 5, co-authored 8 publications receiving 99 citations.

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Unusual localization and translocation of TRPV4 protein in cultured ventricular myocytes of the neonatal rat

TL;DR: It is shown that TRPV4 protein was predominantly located in the nucleus of cultured neonatal myocytes, and cardiac myocytes responded to hypotonic stimulation by translocating TRPv4 protein out of the nucleus.
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TRPC1 expression and distribution in rat hearts

TL;DR: Examination of the expression patterns of TRPC1 in detail in rat hearts suggested that it plays an important role in the heart, and specific distribution pattern offered a useful insight into its function in adult rat ventricular cells.
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Pro-arrhythmic action of autoantibodies against the second extracellular loop of β1-adrenoceptor and its underlying molecular mechanisms

TL;DR: It is demonstrated for the first time that β1-AAbs could directly induce ventricular arrhythmia by prolonging QT interval and can be inhibited byβ1-AR blocker metoprolol.
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The role of NO-cGMP pathway inhibition in vascular endothelial-dependent smooth muscle relaxation disorder of AT1-AA positive rats: protective effects of adiponectin.

TL;DR: Assessment of the mechanism of vascular endothelial-dependent smooth muscle relaxation disorder induced by AT1-AA and the role of adiponectin in attenuating this dysregulation established that impairment NO-cGMP pathway may aggravate the endothelium-dependent Smooth Muscle Relaxation Disorder in AT2-AA positive rats.
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Autoantibody against β 1 -adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4 + T cells by up-regulating AMPK-mediated fatty acid oxidation

TL;DR: AMPK-mediated metabolic regulation targeting for nTreg cell restoration may be a promising therapeutic target for β1-AA-positive patients with cardiac dysfunction.