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Showing papers in "International Journal of Cardiology in 2015"


Journal ArticleDOI
TL;DR: Exo(GATA-4) upon transplantation in the damaged tissue mediate protection by releasing multiple miRs responsible for activation of the cell survival signaling pathway.

365 citations


Journal ArticleDOI
TL;DR: In this paper, the authors investigated if the Fitbit®, one of the most common wireless physical activity trackers in the consumer market, met reasonable validity and reliability standards such that they could be used by primary care physicians to monitor their patient's physical activity objectively between clinic visits.

358 citations


Journal ArticleDOI
TL;DR: Exosomes/microvesicles secreted by iPS cells are very effective at transmitting cytoprotective signals to cardiomyocytes in the setting of MIR, and represent novel biological nanoparticles that offer the benefits of iPS cell therapy without the risk of tumorigenicity.

335 citations


Journal ArticleDOI
TL;DR: The accuracy of death records in the NHIRD was high, and appears to be a valid resource for population research in cardiovascular diseases.

245 citations


Journal ArticleDOI
TL;DR: The proportion of acute coronary syndromes attributed to takotsubo syndrome in Western Sweden has increased over the last decade, with similar early and late mortality as STEMI and NSTEMI.

243 citations


Journal ArticleDOI
TL;DR: Comparing the effects of AIT and Aerobic Continuous Training on peak VO₂, peripheral endothelial function, cardiovascular risk factors, quality of life and safety, in a large multicentre study of coronary artery disease patients observed similar improvements in exercise capacity and peripheral endothelium function.

239 citations


Journal ArticleDOI
TL;DR: The global burden of CV disease, status of secondary prevention therapy and major barriers for treatment adherence are reviewed, showing large gaps between indicated therapy and prescribed medication can be observed worldwide.

213 citations




Journal ArticleDOI
TL;DR: Repeated RIC reduces adverse LV remodeling and oxidative stress by MI, and exosome-mediated intercellular communication may contribute to the beneficial effect of RIC treatment.

148 citations


Journal ArticleDOI
TL;DR: Understanding of mechanisms of macrophages plasticity and resolving functional characteristics of distinct macrophage phenotypes should help in the development of new strategies for treatment of chronic inflammation in atherosclerosis and other cardiovascular diseases.

Journal ArticleDOI
TL;DR: It is suggested that NOACs should be preferentially indicated for stroke prevention in Asians with AF.

Journal ArticleDOI
TL;DR: Total fruit and vegetable, fruit and vegetables consumption, are significantly associated with a lower risk of CHD, and a significant inverse association was observed in Western populations, but not in Asian populations.

Journal ArticleDOI
TL;DR: A systematic review helps differentiate "cognitive impairment" into mild cognitive impairment, dementia, and delirium and assesses the utility of the different screening modalities and their efficacy as they pertain to recognizing cognitive impairment.

Journal ArticleDOI
TL;DR: Positive psychological constructs appear to be prospectively associated with health outcomes in most but not all studies, and additional work is needed to identify which constructs are most important to cardiac health, and whether interventions can cultivate positive attributes and improve clinical outcomes.

Journal ArticleDOI
TL;DR: Despite a greater CAC increase with high dose and long-term statin therapy, events did not occur more frequently in statin treated patients, which suggests that CAC growth under treatment with statins represents plaque repair rather than continuing plaque expansion.


Journal ArticleDOI
TL;DR: Hypertension is highly prevalent in mainland China, with inadequate awareness, treatment, and control of hypertension, and effective strategies are urgently needed in China, especially in the regions with high prevalence and low control.


Journal ArticleDOI
TL;DR: Both general and cardiovascular death risks as well as thromboembolic risk do not seem to be affected by the asymptomatic clinical status and Symptomatic status should not determine the approach to stroke prevention and other cardiovascular prevention therapies, amongst patients with AF.

Journal ArticleDOI
TL;DR: The mechanisms via which pericytes are involved in disease onset and development in a number of pathophysiological conditions are discussed, as well as the evidence that supports a role for multipotentpericytes in tissue regeneration is presented.

Journal ArticleDOI
TL;DR: A weighted meta-analysis revealed that successful recanalization of a CTO resulted in an overall improvement of 4.44% absolute LVEF points, reduced adverse remodeling and an improvement of survival.

Journal ArticleDOI
TL;DR: Reprogramming or optimization of SVT treatment after the first clinical event of inappropriate shock was successful in preventing further inappropriate shocks for cardiac oversensing and SVT events, and programming the primary vector for sensing reduced the risk.

Journal ArticleDOI
TL;DR: SIRT1 may attenuate ER stress-induced cardiomyocyte apoptosis via PERK/eIF2α, ATF6/CHOP, and IRE1α/JNK-mediated pathways, and a SIRT1 activator, resveratrol, could significantly restore cardiac function, reduceCardiomyocytes apoptosis, and ameliorate ER stress.

Journal ArticleDOI
TL;DR: A panel of 34 experts in the field of cardiology and intensive cardiac care from 21 countries around the world convened for reviewing the existing data on quality of life in patients with advanced heart failure, discussing and reaching a consensus on the validity and significance of quality-of-life assessment methods.

Journal ArticleDOI
TL;DR: The burden of CVD and its related risk factors is at emerging rates, in Greece, making the need for effective public health actions, more necessary than ever before.

Journal ArticleDOI
TL;DR: A person-centred care approach emphasising the partnership between patients and health care professionals throughout the care chain improves general self-efficacy without causing worsening clinical events.

Journal ArticleDOI
TL;DR: Treatment with eplerenone has been associated with decreased blood pressure and improved survival for patients with heart failure and reduced left ventricular ejection fraction, and severe adverse effects such as gynecomastia and vaginal bleeding seem to be less likely in patients who take epleRenone than in those who take spironolactone.

Journal ArticleDOI
TL;DR: On the last decade, there has been a progressive increase in a number of publications on microbiota and therapeutic potential of probiotics, suggesting that consuming probiotics may have benefits on cardiovascular system, as the improvement on blood pressure control by a modest degree.

Journal ArticleDOI
TL;DR: The current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention are described.