Y
Yuichi Goto
Researcher at Kagoshima University
Publications - 67
Citations - 964
Yuichi Goto is an academic researcher from Kagoshima University. The author has contributed to research in topics: Mitochondrial myopathy & Mitochondrial DNA. The author has an hindex of 16, co-authored 67 publications receiving 787 citations. Previous affiliations of Yuichi Goto include Kyushu University.
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Journal ArticleDOI
Increased expression of interleukin-6 predicts poor response to chemoradiotherapy and unfavorable prognosis in oral squamous cell carcinoma.
Teppei Jinno,Shintaro Kawano,Yasuyuki Maruse,Ryota Matsubara,Yuichi Goto,Taiki Sakamoto,Yuma Hashiguchi,Naoki Kaneko,Hideaki Tanaka,Ryoji Kitamura,Takeshi Toyoshima,Akiko Jinno,Masafumi Moriyama,Kazunari Oobu,Tamotsu Kiyoshima,Seiji Nakamura +15 more
TL;DR: IL-6 signaling possibly is involved in the progression and treatment-resistance of OSCC and IL-6 expression in cancer cells could be a useful predictive factor of poor response to chemoradiotherapy and unfavorable prognosis.
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Association of cytokeratin 17 expression with differentiation in oral squamous cell carcinoma.
Ryoji Kitamura,Takeshi Toyoshima,Hideaki Tanaka,Shintaro Kawano,Takahiro Kiyosue,Ryota Matsubara,Yuichi Goto,Mitsuhiro Hirano,Kazunari Oobu,Seiji Nakamura +9 more
TL;DR: CK17 expression could be associated with the differentiation and the malignancy of OSCC and a combination pattern of CK17/CK13 might be a suitable marker of malignant transformation.
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Significant association of increased PD-L1 and PD-1 expression with nodal metastasis and a poor prognosis in oral squamous cell carcinoma.
Yasuyuki Maruse,Shintaro Kawano,Teppei Jinno,Ryota Matsubara,Yuichi Goto,Naoki Kaneko,Taiki Sakamoto,Yuma Hashiguchi,Masafumi Moriyama,Takeshi Toyoshima,Ryoji Kitamura,H. Tanaka,Kazunari Oobu,Tamotsu Kiyoshima,Seiji Nakamura +14 more
TL;DR: Data suggest that increased PD-L1 and PD-1 expression is predictive of nodal metastasis and a poor prognosis and is possibly involved in cancer progression via attenuating the immune response.
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Novel variants of the SHANK3 gene in Japanese autistic patients with severe delayed speech development.
Chikako Waga,Nobuhiko Okamoto,Yumiko Ondo,Reiko Fukumura-Kato,Yuichi Goto,Shinichi Kohsaka,Shigeo Uchino +6 more
TL;DR: The SHANK3 gene was analyzed in 128 autistic patients with manifestations similar to those seen in the 22q13.3 deletion syndrome and showed a 6-amino acid deletion upstream of the SH3 domain, a missense variant in the PDZ domain, and the insertion or deletion of a repeated 10-bp GC sequence located 9-bp downstream from the 3′ end of exon 11.
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The diagnostic utility of biopsies from the submandibular and labial salivary glands in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease.
Masafumi Moriyama,Sachiko Furukawa,Shintaro Kawano,Yuichi Goto,Tamotsu Kiyoshima,Akihiko Tanaka,Takashi Maehara,Jun Nosuke Hayashida,Miho Ohta,Seiji Nakamura +9 more
TL;DR: Examination of the diagnostic utility of submandibular gland (SMG) and labial salivary gland (LSG) biopsies in IgG4-DS suggests that incisional biopsy of the SMG is useful and appropriate for the definitive diagnosis of IgG 4-DS, while diagnosis by LSG biopsy alone requires more caution.