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Yuichiro J. Suzuki
Researcher at Georgetown University Medical Center
Publications - 133
Citations - 13052
Yuichiro J. Suzuki is an academic researcher from Georgetown University Medical Center. The author has contributed to research in topics: Pulmonary hypertension & Signal transduction. The author has an hindex of 39, co-authored 131 publications receiving 11979 citations. Previous affiliations of Yuichiro J. Suzuki include United States Department of Agriculture & Georgetown University.
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Differential regulation of MAP kinase signaling by pro- and antioxidant biothiols.
TL;DR: In cells grown in serum, serum‐dependent p44/42 MAPK phosphorylation was transiently enhanced by Hcy or Hcy thiolactone, but inhibited by αLA, which may be important in understanding how some biothiols are associated with pathogenic events while others have potential as therapeutic agents.
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Superoxide Generated by Cigarette Smoke Damages the Respiratory Burst and Induces Physical Changes in the Membrane Order and Water Organization of Inflammatory Cells
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Relationships between the effects of superoxide anion and palmitoyl-L-carnitine on the Ca2+-ATPase of vascular smooth muscle sarcoplasmic reticulum
TL;DR: It is demonstrated that O2- can inhibit stimulatory effects of PLC on the Ca(2+)-ATPase, however, PLC does not block the inhibitory effect of O2-.
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Effects of Bcl-2/Bcl-xL Inhibitors on Pulmonary Artery Smooth Muscle Cells.
TL;DR: Promoting apoptosis by inhibiting anti-apoptotic B cl-2 and Bcl-xL effectively kills pulmonary vascular smooth muscle cells and reverses pulmonary vascular remodeling.
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The viral protein fragment theory of COVID-19 pathogenesis
TL;DR: It is proposed that cell signaling elicited by the spike protein fragment that occurs on cardiovascular cells would predispose infected individuals to develop complications that are seen in severe and fatal COVID-19 conditions.