Y
Yujiao Yin
Researcher at Tongji University
Publications - 8
Citations - 370
Yujiao Yin is an academic researcher from Tongji University. The author has contributed to research in topics: Deubiquitinating enzyme & DNA repair. The author has an hindex of 5, co-authored 8 publications receiving 268 citations.
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Journal ArticleDOI
CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1
Tongzheng Liu,Jia Yu,Min Deng,Yujiao Yin,Haoxing Zhang,Kuntian Luo,Kuntian Luo,Bo Qin,Yunhui Li,Chenming Wu,Tao Ren,Yang Han,Peng Yin,Jung Jin Kim,Seung Baek Lee,Jing Lin,Lizhi Zhang,Jun Zhang,Somaira Nowsheen,Liewei Wang,Judy C. Boughey,Matthew P. Goetz,Jian Yuan,Jian Yuan,Zhenkun Lou +24 more
TL;DR: Overall, this study establishes the CDK4/6–DUB3 axis as an important regulatory mechanism of breast cancer metastasis and provides a rationale for potential therapeutic interventions in the treatment of breast Cancer metastasis.
Journal ArticleDOI
USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51‐AKT signaling
Kuntian Luo,Kuntian Luo,Yunhui Li,Yujiao Yin,Lei Li,Chenming Wu,Yuping Chen,Somaira Nowsheen,Qi Hu,Lizhi Zhang,Zhenkun Lou,Jian Yuan,Jian Yuan +12 more
TL;DR: The findings establish USP49 as a novel regulator of AKT pathway with a critical role in tumorigenesis and chemo‐response in pancreatic cancer.
Journal ArticleDOI
A phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination.
Kuntian Luo,Lei Li,Yunhui Li,Chenming Wu,Yujiao Yin,Yuping Chen,Min Deng,Somaira Nowsheen,Jian Yuan,Jian Yuan,Zhenkun Lou +10 more
TL;DR: UCHL3 is identified as a novel regulator of DNA repair and a model in which a phosphorylation-deubiquitination cascade dynamically regulates the BRCA2-RAD51 pathway is revealed, which is critical for proper HR.
Journal ArticleDOI
USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response.
Yunhui Li,Kuntian Luo,Kuntian Luo,Yujiao Yin,Chenming Wu,Min Deng,Lei Li,Yuping Chen,Somaira Nowsheen,Zhenkun Lou,Jian Yuan,Jian Yuan +11 more
TL;DR: Overall, USP13 is identified as a regulator of DNA repair and a model in which a phosphorylation-deubiquitination axis dynamically regulates RAP80-BRCA1 complex foci formation and function is revealed.
Journal ArticleDOI
The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization.
Lei Li,Tongzheng Liu,Yunhui Li,Chenming Wu,Kuntian Luo,Kuntian Luo,Yujiao Yin,Yuping Chen,Somaira Nowsheen,Jinhuan Wu,Zhenkun Lou,Jian Yuan,Jian Yuan +12 more
TL;DR: It is demonstrated that the deUBiquitination enzyme USP9X deubiquitinates and stabilizes YAP1, thereby promoting cancer cell survival and establishes the USP 9X-YAP1 axis as an important regulatory mechanism of breast cancer and provides a rationale for potential therapeutic interventions in the treatment of Breast cancer.