Y
Yujiro Hoshino
Researcher at Yokohama National University
Publications - 78
Citations - 1754
Yujiro Hoshino is an academic researcher from Yokohama National University. The author has contributed to research in topics: Catalysis & Cycloaddition. The author has an hindex of 16, co-authored 76 publications receiving 1569 citations. Previous affiliations of Yujiro Hoshino include University of Chicago & Kyoto University.
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Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite
Tetsuro Fujita,Kenichiro Inoue,Kenichiro Inoue,Satoshi Yamamoto,Satoshi Yamamoto,T. Ikumoto,Shigeo Sasaki,R. Toyama,Kenji Chiba,Yujiro Hoshino,T. Okumoto +10 more
TL;DR: The metabolite, ISP-I, was 10- to 100-fold more potent than cyclosporin A as an immunosuppressive agent of the immune response in vitro and in vivo, and appears to be a candidate for clinical application as a powerful Immunosuppressant.
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Enantioselective Epoxidation of Allylic Alcohols by a Chiral Complex of Vanadium: An Effective Controller System and a Rational Mechanistic Model
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Asymmetric ene reaction catalyzed by chiral organoaluminum reagent
TL;DR: In this paper, the asymmetric ene reaction of prochiral aldehydes with alkenes has been effected by chiral organoaluminum reagent providing optically active homoallylic alcohols in both enantiomeric forms with high enantiomic purity.
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Fungal Metabolites. Part 11. A Potent Immunosuppressive Activity Found in Isaria sinclairii Metabolite.
Tetsuro Fujita,Kenichiro Inoue,Satoshi Yamamoto,T. Ikumoto,Shigeo Sasaki,R. Toyama,Kenji Chiba,Yujiro Hoshino,T. Okumoto +8 more
TL;DR: In this article, ISP-I ((2S,3R,4R)-(E)-2-amino-3,4-dihydroxy-2- hydroxymethyl-14-oxoeicos-6-enoic acid, myriocin = thermozymocidin) was found to suppress the proliferation of lymphocytes in mouse allogeneic mixed lymphocyte reaction, but had no effect on the growth of human tumor cell lines.
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FUNGAL METABOLITES. PART 14†. NOVEL POTENT IMMUNOSUPPRESSANTS, MYCESTERICINS, PRODUCED BY Mycelia sterilia
Shigeo Sasaki,Ryouta Hashimoto,Masatoshi Kiuchi,Kenichiro Inoue,Kenichiro Inoue,T. Ikumoto,Ryoji Hirose,Kenji Chiba,Yujiro Hoshino,T. Okumoto,Tetsuro Fujita +10 more
TL;DR: Mycestericins suppressed the proliferation of lymphocytes in the mouse allogeneic mixed lymphocyte reaction, with a potency similar to that of myriocin.