Y
Yul Huh
Researcher at Duke University
Publications - 13
Citations - 1178
Yul Huh is an academic researcher from Duke University. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 5, co-authored 8 publications receiving 518 citations.
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Journal ArticleDOI
Neuroinflammation and Central Sensitization in Chronic and Widespread Pain
TL;DR: Neuroinflammation drives widespread chronic pain via central sensitization and sex-dependent glial/immune signaling in chronic pain and new therapeutic approaches that control neuroinflammation for the resolution of chronic pain are discussed.
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Roles of inflammation, neurogenic inflammation, and neuroinflammation in pain.
TL;DR: The distinct roles of inflammation, neurogenic inflammation, and neuro inflammation in the regulation of different types of pain conditions are discussed, with a special focus on neuroinflammation in postoperative pain and opioid-induced hyperalgesia.
Journal ArticleDOI
Neuroinflammation, Bone Marrow Stem Cells, and Chronic Pain.
Yul Huh,Ru-Rong Ji,Gang Chen +2 more
TL;DR: BMSCs exhibit potent modulation of neuroinflammation, by inhibiting monocyte infiltration, glial activation, and cytokine/chemokine production in the DRG and spinal cord, and thereby control chronic pain by regulation of neuro inflammation in the PNS and CNS via paracrine signaling.
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Macrophage Toll-like Receptor 9 Contributes to Chemotherapy-Induced Neuropathic Pain in Male Mice
TL;DR: It is shown that macrophage TLR9 signaling promotes CIPN in male mice only, which suggests that pathways in macrophages may be sex-dimorphic in CIPn.
Journal ArticleDOI
IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice.
Xin Luo,Ouyang Chen,Zilong Wang,Sangsu Bang,Jasmine Ji,Sang Hoon Lee,Yul Huh,Kenta Furutani,Qianru He,Xueshu Tao,Mei-Chuan Ko,Andrey V. Bortsov,Christopher R. Donnelly,Yong Chen,Andrea G. Nackley,Temugin Berta,Ru-Rong Ji +16 more
TL;DR: In this paper, the IL-23/IL-17A/TRPV1 axis regulates female-specific mechanical pain via neuro-immune interactions and reveals sex dimorphism at both immune and neuronal levels.