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Yun Cui

Researcher at Nankai University

Publications -  7
Citations -  809

Yun Cui is an academic researcher from Nankai University. The author has contributed to research in topics: Controlled release & Prodrug. The author has an hindex of 6, co-authored 7 publications receiving 649 citations.

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Effect of sustained heparin release from PCL/chitosan hybrid small-diameter vascular grafts on anti-thrombogenic property and endothelialization.

TL;DR: Results indicate that sustained release of heparin provided optimal anti-thrombogenic effect by reducing thrombus formation and maintaining the patency of the PCL/CS vascular grafts, and enhanced in situ endothelialization, thereby preventing the occurrence of restenosis.
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Polysaccharide-based biomaterials with on-demand nitric oxide releasing property regulated by enzyme catalysis

TL;DR: A stable comb-shaped polymer (CS-NO) using glycosylated NO compound as pendent chains and chitosan (CS) as backbone for controlled NO release is reported, demonstrating its clinical potential and physiological importance of NO.
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Enzyme-functionalized vascular grafts catalyze in-situ release of nitric oxide from exogenous NO prodrug.

TL;DR: An enzyme-functionalized vascular graft is created that can catalyze prodrug to release NO locally and sustainably, indicating that this approach may be useful to develop new cell-free vascular grafts for treatment of vascular diseases.
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Enhanced vascularization in hybrid PCL/gelatin fibrous scaffolds with sustained release of VEGF.

TL;DR: In vivo subcutaneous implantation reflects that vascularization has been effectively enhanced in the heparinized PCL/gelatin scaffolds compared with the PCL counterpart due to the sustained release of VEGF, which may be a promising candidate for regeneration of complex tissues with sufficient vascularization.