Y
Yun Feng
Researcher at Tongji University
Publications - 17
Citations - 1131
Yun Feng is an academic researcher from Tongji University. The author has contributed to research in topics: Transcriptome & Gene. The author has an hindex of 9, co-authored 14 publications receiving 908 citations.
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Journal ArticleDOI
Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing
Zhigang Xue,Kevin Huang,Chaochao Cai,Lingbo Cai,Chunyan Jiang,Yun Feng,Zhenshan Liu,Qiao Zeng,Liming Cheng,Yi E. Sun,Jiayin Liu,Steve Horvath,Guoping Fan +12 more
TL;DR: A comprehensive analysis of transcriptome dynamics from oocyte to morula in both human and mouse embryos, using single-cell RNA sequencing finds that each developmental stage can be delineated concisely by a small number of functional modules of co-expressed genes.
Journal ArticleDOI
Assessing the elastic properties of skeletal muscle and tendon using shearwave ultrasound elastography and MyotonPRO.
TL;DR: It is suggested that the resting stiffness of gastrocnemius muscle belly and Achilles tendon measured by MyotonPRO is related to the Young’s modulus of those quantified by SWUE, and the Myoton PRO shows good intra-operator repeatability.
Journal ArticleDOI
Single-cell analysis of differences in transcriptomic profiles of oocytes and cumulus cells at GV, MI, MII stages from PCOS patients
Qiwei Liu,Yumei Li,Yun Feng,Chaojie Liu,Jieliang Ma,Yifei Li,Huifen Xiang,Yazhong Ji,Yunxia Cao,Xiaowen Tong,Zhigang Xue +10 more
TL;DR: ARTs can improve the quality of cumulus-oocyte complex (COC) and increase the ratio of fertilization and cleavage in PCOS women, and assess the effectiveness of ARTs in treating PCOS patients.
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Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient during neuronal differentiation.
Ping Lu,Xiao-Long Chen,Yun Feng,Qiao Zeng,Cizhong Jiang,Xianmin Zhu,Guoping Fan,Guoping Fan,Zhigang Xue +8 more
TL;DR: It is demonstrated that the FMRP deficiency in FXS patients has significant impact on the gene expression patterns during development, which will help to discover potential targeting candidates for the cure of FXS symptoms.
Journal ArticleDOI
Integrated Analysis of DNA Methylation and RNA Transcriptome during In Vitro Differentiation of Human Pluripotent Stem Cells into Retinal Pigment Epithelial Cells
Zhenshan Liu,Rongfeng Jiang,Songtao Yuan,Na Wang,Yun Feng,Ganlu Hu,Xianmin Zhu,Kevin Huang,Jieliang Ma,Guo-Tong Xu,Qinghuai Liu,Zhigang Xue,Guoping Fan +12 more
TL;DR: The results demonstrate that DNA methylation may serve as biomarkers to characterize the cell differentiation process during the conversion of human pluripotent stem cells into functional RPE cells.