Y
Yunbo Li
Researcher at Campbell University
Publications - 9
Citations - 422
Yunbo Li is an academic researcher from Campbell University. The author has contributed to research in topics: Cell adhesion molecule & ICAM-1. The author has an hindex of 6, co-authored 9 publications receiving 354 citations. Previous affiliations of Yunbo Li include Virginia Tech & Wake Forest University.
Papers
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Journal ArticleDOI
Luteolin protects against vascular inflammation in mice and TNF-alpha-induced monocyte adhesion to endothelial cells via suppressing IΚBα/NF-κB signaling pathway
Zhenquan Jia,Palanisamy Nallasamy,Dongmin Liu,Halley Shah,Jason Z. Li,Rojin Chitrakar,Hongwei Si,John McCormick,Hong Zhu,Wei Zhen,Yunbo Li,Yunbo Li +11 more
TL;DR: It is reported that luteolin as low as 0.5 μM significantly inhibited tumor necrosis factor (TNF)-α-induced adhesion of monocytes to human EA and preserved elastin fibers' delicate organization as shown by Verhoeff-Van Gieson staining.
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NAD(P)H:Quinone Oxidoreductase 1 and its Potential Protective Role in Cardiovascular Diseases and Related Conditions
TL;DR: This review is intended to summarize the recent development regarding the biochemical properties and molecular regulation of NQO1 and its potential beneficial role in cardiovascular diseases and related conditions, including metabolic syndrome.
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Genistein inhibits TNF-α-induced endothelial inflammation through the protein kinase pathway A and improves vascular inflammation in C57BL/6 mice.
Zhenquan Jia,Pon Velayutham Anandh Babu,Hongwei Si,Palanisamy Nallasamy,Hong Zhu,Wei Zhen,Hara P. Misra,Yunbo Li,Dongmin Liu +8 more
TL;DR: It is reported that genistein at physiological concentrations significantly inhibited TNF-α-induced adhesion of monocytes to human umbilical vein endothelial cells, a key event in the pathogenesis of atherosclerosis.
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Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway
Palanisamy Nallasamy,Hongwei Si,Pon Velayutham Anandh Babu,Dengke Pan,Yu Fu,Elizabeth A.S. Brooke,Halley Shah,Wei Zhen,Hong Zhu,Dongmin Liu,Yunbo Li,Zhenquan Jia +11 more
TL;DR: Sulforaphane at physiological concentrations protects against TNF-α-induced vascular endothelial inflammation, in both in vitro and in vivo models, suggesting that sul foraphane can inhibit inflammation by suppressing NF-κB signaling.
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The antioxidant enzyme peroxiredoxin and its protective role in neurological disorders.
TL;DR: The biochemical properties and molecular regulation of Prxs are described, the major findings on the neuroprotective functions of Prx are summarized, and the feasibility of using natural compounds, including those from herbal remedies to augment Prx expression to counteract oxidative neurological disorders is discussed.