H
Halley Shah
Researcher at University of North Carolina at Greensboro
Publications - 4
Citations - 232
Halley Shah is an academic researcher from University of North Carolina at Greensboro. The author has contributed to research in topics: Cell adhesion molecule & ICAM-1. The author has an hindex of 4, co-authored 4 publications receiving 188 citations.
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Journal ArticleDOI
Luteolin protects against vascular inflammation in mice and TNF-alpha-induced monocyte adhesion to endothelial cells via suppressing IΚBα/NF-κB signaling pathway
Zhenquan Jia,Palanisamy Nallasamy,Dongmin Liu,Halley Shah,Jason Z. Li,Rojin Chitrakar,Hongwei Si,John McCormick,Hong Zhu,Wei Zhen,Yunbo Li,Yunbo Li +11 more
TL;DR: It is reported that luteolin as low as 0.5 μM significantly inhibited tumor necrosis factor (TNF)-α-induced adhesion of monocytes to human EA and preserved elastin fibers' delicate organization as shown by Verhoeff-Van Gieson staining.
Journal ArticleDOI
Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway
Palanisamy Nallasamy,Hongwei Si,Pon Velayutham Anandh Babu,Dengke Pan,Yu Fu,Elizabeth A.S. Brooke,Halley Shah,Wei Zhen,Hong Zhu,Dongmin Liu,Yunbo Li,Zhenquan Jia +11 more
TL;DR: Sulforaphane at physiological concentrations protects against TNF-α-induced vascular endothelial inflammation, in both in vitro and in vivo models, suggesting that sul foraphane can inhibit inflammation by suppressing NF-κB signaling.
Journal ArticleDOI
Protection of HepG2 cells against acrolein toxicity by 2-cyano-3,12-dioxooleana-1,9-dien-28-imidazolide via glutathione-mediated mechanism.
Halley Shah,Adam M Speen,Christina Saunders,Elizabeth A.S. Brooke,Palanisamy Nallasamy,Hong Zhu,Y. Robert Li,Y. Robert Li,Zhenquan Jia +8 more
TL;DR: GSH is a predominant mechanism underlying acrolein-induced cytotoxicity as well as CDDO-Im-mediated cytoprotection, which may provide understanding on the molecular action of acroleIn which may be important to develop novel strategies for the prevention of ac Rolein-mediated toxicity.
Journal ArticleDOI
Mechanisms of CDDO-imidazolide-mediated cytoprotection against acrolein-induced neurocytotoxicity in SH-SY5Y cells and primary human astrocytes
Adam M Speen,Colton Jones,Ruby Patel,Halley Shah,Palanisamy Nallasamy,Elizabeth A.S. Brooke,Hong Zhu,Y. Robert Li,Zhenquan Jia +8 more
TL;DR: This study represents for the first time the CDDO-Im mediated upregulation of GSH is a predominant mechanism against acrolein-induced neurotoxicity.