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Yunn-Fang Ho

Researcher at National Taiwan University

Publications -  38
Citations -  2632

Yunn-Fang Ho is an academic researcher from National Taiwan University. The author has contributed to research in topics: Apoptosis & Medicine. The author has an hindex of 16, co-authored 32 publications receiving 2428 citations. Previous affiliations of Yunn-Fang Ho include National Yang-Ming University.

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Journal Article

Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions.

TL;DR: It is demonstrated that curcumin is not toxic to humans up to 8,000 mg/day when taken by mouth for 3 months and a biologic effect ofCurcumin in the chemoprevention of cancer is suggested.
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Determination and pharmacokinetic profile of omeprazole in rat blood, brain and bile by microdialysis and high-performance liquid chromatography.

TL;DR: The decline of unbound omeprazole in the brain striatum, blood and bile fluid suggests that there was rapid exchange and equilibration between the compartments of the peripheral and central nervous systems and indicates that omepazole was able to penetrate the blood-brain barrier and undergo hepatobiliary excretion.
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The COMT L allele modifies the association between MAOB polymorphism and PD in Taiwanese.

TL;DR: The results suggest that, in Taiwanese, PD risk is associated with MAOB G intron 13 polymorphism, and this association is augmented in the presence of the COMTL genotype, indicating an interaction of these two dopamine-metabolizing enzymes in the pathogenesis of sporadic PD.
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Lipid-mediated preferential localization of hypericin in lipid membranes.

TL;DR: The data lead to the conclusion that cholesterol is the major origin of the selectivity for hypericin in membrane systems.
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Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.

TL;DR: It is suggested that 2-phenyl-4-quinolone displays anticancer effect through the dysregulation of mitotic spindles and induction of mitotics arrest in cancer types through which it displayed anti-proliferative effect.