Yutaka Shimada

TL;DR: It is suggested that PTTG1 overexpression promotes cell motility and lymph node metastasis in ESCC patients, leading to poorer survival and global gene expression profiling suggested that several members of the Ras and Rho gene families represented potential downstream genes in the PTTGs pathway.

TL;DR: The discovery of a novel member of this class, ZASC1, from a recently reported critical region of 3q26 amplification frequently observed in various squamous cell carcinomas is reported, suggesting that Zasc1 might be involved in the pathogenesis of ESC as one of the targets for 3q 26 amplification, alone or in concert with other targets.

TL;DR: The results suggest that OGT and KBG prevent the progression of atheromatous plaque by creating a sounder antioxidant defense system than vitamin E.

TL;DR: Many studies have attempted to detect cancer cells using the reverse transcription–polymerase chain reaction for specific mRNAs, but none has examined the correlation between the presence of circulating oesophageal cancer cells in peripheral blood and long‐term outcome.

TL;DR: TSOD male mice spontaneously developed NAFLD without any special treatment, and that these mice are a valuable model for assessing NASH and NASH carcinogenesis owing to metabolic syndrome are reported.