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Yvonne de Kozak
Researcher at French Institute of Health and Medical Research
Publications - 44
Citations - 2216
Yvonne de Kozak is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Antibody & Uveitis. The author has an hindex of 26, co-authored 44 publications receiving 1958 citations. Previous affiliations of Yvonne de Kozak include Paris Descartes University & Pierre-and-Marie-Curie University.
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Journal ArticleDOI
Mechanisms of macular edema: Beyond the surface.
Alejandra Daruich,Alexandre Matet,Alexandre Moulin,Laura Kowalczuk,Michael Nicolas,Alexandre Sellam,Pierre-Raphaël Rothschild,Samy Omri,Emmanuelle Gelize,Laurent Jonet,Kimberley Delaunay,Yvonne de Kozak,Marianne Berdugo,Min Zhao,Patricia Crisanti,Francine Behar-Cohen,Francine Behar-Cohen +16 more
TL;DR: This comprehensive review on the current understanding of macular edema and its mechanisms opens perspectives to identify new preventive and therapeutic strategies for this sight-threatening condition.
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Microglia/Macrophages Migrate through Retinal Epithelium Barrier by a Transcellular Route in Diabetic Retinopathy: Role of PKCζ in the Goto Kakizaki Rat Model
Samy Omri,Samy Omri,Samy Omri,Francine Behar-Cohen,Yvonne de Kozak,Yvonne de Kozak,Yvonne de Kozak,Florian Sennlaub,Florian Sennlaub,Florian Sennlaub,Lourena Mafra Verissimo,Laurent Jonet,Laurent Jonet,Laurent Jonet,Michèle Savoldelli,Boubaker Omri,Boubaker Omri,Boubaker Omri,Patricia Crisanti,Patricia Crisanti,Patricia Crisanti +20 more
TL;DR: It is shown here that a physiological transcellular pathway takes place through RPE cells and contributes to microglia/macrophages retinal trafficking and Chronic hyperglycemia causes alteration of this pathway and subsequent subretinal accumulation of activated microglIA/ Macrophages.
Journal ArticleDOI
Intraocular injection of tamoxifen-loaded nanoparticles: a new treatment of experimental autoimmune uveoretinitis
Yvonne de Kozak,Karine Andrieux,Henri Villarroya,Christophe Klein,B. Thillaye-Goldenberg,Marie-Christine Naud,Elisabeth Garcia,Patrick Couvreur +7 more
TL;DR: Intravitreal injection of NP‐PEG‐TAM decreased S‐Ag lymphocyte proliferation, IFN‐γ production by inguinal lymph node cells, and specific delayed‐type hypersensitivity indicative of a reduced Th1‐type response and increased the anti‐S‐Ag IgG1 isotype indicating an antibody class switch to Th2 response.
Journal ArticleDOI
Induction and Regulation of Nitric Oxide Synthase in Retinal Müller Glial Cells
TL;DR: It is concluded that RMG cells can express an inducible form of NOS similar to the macrophage isoform, which might represent a protection from infection but may also contribute to the development of retinal pathologies.
Journal ArticleDOI
Iontophoresis of dexamethasone in the treatment of endotoxin-induced uveitis in rats
Francine Behar-Cohen,Jean-Marie A. Parel,Jean-Marie A. Parel,Yves Pouliquen,Beatrice Thillaye-Goldenberg,Olivier Goureau,Silke Heydolph,Yves Courtois,Yvonne de Kozak +8 more
TL;DR: CCI administration of Dex allows for a therapeutic effect on the posterior as well as the anterior segment of the eye, and may present a viable alternative to systemic administration of glucocorticoids in severe ocular inflammations.