A
Alexandre Moulin
Researcher at University of Lausanne
Publications - 86
Citations - 2434
Alexandre Moulin is an academic researcher from University of Lausanne. The author has contributed to research in topics: Retinoblastoma & Medicine. The author has an hindex of 22, co-authored 79 publications receiving 1852 citations. Previous affiliations of Alexandre Moulin include University Hospital of Lausanne & French Institute of Health and Medical Research.
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Journal ArticleDOI
Mechanisms of macular edema: Beyond the surface.
Alejandra Daruich,Alexandre Matet,Alexandre Moulin,Laura Kowalczuk,Michael Nicolas,Alexandre Sellam,Pierre-Raphaël Rothschild,Samy Omri,Emmanuelle Gelize,Laurent Jonet,Kimberley Delaunay,Yvonne de Kozak,Marianne Berdugo,Min Zhao,Patricia Crisanti,Francine Behar-Cohen,Francine Behar-Cohen +16 more
TL;DR: This comprehensive review on the current understanding of macular edema and its mechanisms opens perspectives to identify new preventive and therapeutic strategies for this sight-threatening condition.
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Intravitreal chemotherapy for vitreous disease in retinoblastoma revisited: from prohibition to conditional indications
Francis L. Munier,Marie-Claire Gaillard,Aubin Balmer,Sameh E. Soliman,Gregory Podilsky,Alexandre Moulin,Maja Beck-Popovic +6 more
TL;DR: Despite a possible confounding effect of concomitant chemotherapy prescription using other routes of administration in four of the successfully treated eyes, IViC achieved an unprecedented success rate of tumour control in the presence of vitreous seeding.
Journal ArticleDOI
Profiling safety of intravitreal injections for retinoblastoma using an anti-reflux procedure and sterilisation of the needle track
Francis L. Munier,Sameh E. Soliman,Alexandre Moulin,Marie-Claire Gaillard,Aubin Balmer,Maja Beck-Popovic +5 more
TL;DR: This technique is potentially safe and effective at a low cost and may play a promising role, especially in the treatment of recurrent and/or resistant vitreous disease in retinoblastoma, as an alternative to enucleation and/ or external beam radiotherapy.
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Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace. "Alive, with good vision and no comorbidity".
Francis L. Munier,Maja Beck-Popovic,Guillermo Chantada,David Cobrinik,Tero Kivelä,Dietmar R. Lohmann,Philippe Maeder,Annette C. Moll,Angel M. Carcaboso,Alexandre Moulin,Paula Schaiquevich,Ciara Bergin,Paul J. Dyson,Susan Houghton,Francesco Puccinelli,Yvan Vial,Marie-Claire Gaillard,Christina Stathopoulos +17 more
TL;DR: This work intends to review the relevant knowledge susceptible to improve the conservative management of retinoblastoma in compliance with the "state of metastatic grace", with particular attention to reviewing how new imaging modalities impact the frontiers of conservative management.
Journal ArticleDOI
Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing
Beryl Royer-Bertrand,Matteo Torsello,Donata Rimoldi,Ikram El Zaoui,Katarina Cisarova,Rosanna Pescini-Gobert,Franck Raynaud,Franck Raynaud,Leonidas Zografos,Ann Schalenbourg,Daniel E. Speiser,Michael Nicolas,Laureen Vallat,Robert J. Klein,Serge Leyvraz,Giovanni Ciriello,Giovanni Ciriello,Nicolo Riggi,Alexandre Moulin,Carlo Rivolta +19 more
TL;DR: In this article, the authors performed whole-genome sequencing at very deep coverage of tumor-control pairs in 33 samples (24 primary and 9 metastases) and found that the number of coding mutations was rather low (only 17 variants per tumor on average; range 7-28).