Z
Zaccharias Cheruvallath
Publications - 1
Citations - 171
Zaccharias Cheruvallath is an academic researcher. The author has contributed to research in topics: Receptor & Farnesoid X receptor. The author has an hindex of 1, co-authored 1 publications receiving 156 citations.
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Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol.
Kerstin Otte,Harald Kranz,Ingo Kober,Paul Thompson,Michael Hoefer,Bernhard Haubold,Bettina Remmel,H. Voss,Carmen Kaiser,Michael Albers,Zaccharias Cheruvallath,David A. Jackson,Georg Casari,Manfred Koegl,Svante Pääbo,Jan Mous,Claus Kremoser,Ulrich Deuschle +17 more
TL;DR: The identification ofFXRβ as a novel functional receptor in nonprimate animals sheds new light on the species differences in cholesterol metabolism and has strong implications for the interpretation of genetic and pharmacological studies of FXR-directed physiologies and drug discovery programs.