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Zachary P. Weiner
Researcher at Centers for Disease Control and Prevention
Publications - 23
Citations - 481
Zachary P. Weiner is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 14 publications receiving 257 citations. Previous affiliations of Zachary P. Weiner include University of Virginia.
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Journal ArticleDOI
SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members - USS Theodore Roosevelt, April 2020.
Daniel C. Payne,Sarah E. Smith-Jeffcoat,Gosia Nowak,Uzo Chukwuma,Jesse R. Geibe,Robert J. Hawkins,Jeffrey A. Johnson,Natalie J. Thornburg,Natalie J. Thornburg,Natalie J. Thornburg,Jarad Schiffer,Zachary P. Weiner,Bettina Bankamp,Michael D. Bowen,P Adam MacNeil,Monita R. Patel,Eric Deussing,Bruce L. Gillingham +17 more
TL;DR: The outbreak was characterized by widespread transmission with relatively mild symptoms and asymptomatic infection among this sample of mostly young, healthy adults with close, congregate exposures and the presence of neutralizing antibodies, which represent antibodies that inhibit SARS-CoV-2, among the majority of those with antibody responses is a promising indicator of at least short-term immunity.
Journal ArticleDOI
Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections
Iuliia M. Gilchuk,Pavlo Gilchuk,Pavlo Gilchuk,Gopal Sapparapu,Rebecca Lampley,Vidisha Singh,Nurgun Kose,David L. Blum,Laura J. Hughes,Panayampalli Subbian Satheshkumar,Michael B. Townsend,Ashley V. Kondas,Zachary Reed,Zachary P. Weiner,Victoria A. Olson,Erika Hammarlund,Hans Peter Raué,Mark K. Slifka,James C. Slaughter,Barney S. Graham,Kathryn M. Edwards,Roselyn J. Eisenberg,Gary H. Cohen,Sebastian Joyce,Sebastian Joyce,James E. Crowe +25 more
TL;DR: This work reveals orthopoxvirus targets for human Abs that mediate cross-protective immunity and identifies new candidate Ab therapeutic mixtures to replace VIG.
Journal ArticleDOI
Updating perspectives on the initiation of Bacillus anthracis growth and dissemination through its host.
Zachary P. Weiner,Ian J. Glomski +1 more
TL;DR: A new “jailbreak” model of B. anthracis dissemination is proposed which applies to the dissemination of all common manifestations of the disease anthrax and impacts the field by deemphasizing the role of host cells as conduits for dissemination and increasing therole of phagocytes as central players in innate defenses, while moving the focus toward interactions between B. Anthracis and lymphoid and epithelial tissues.
Journal ArticleDOI
Circulating lethal toxin decreases the ability of neutrophils to respond to Bacillus anthracis.
Zachary P. Weiner,Stephen M. C. Ernst,Anne E. Boyer,Maribel Gallegos-Candela,John R. Barr,Ian J. Glomski +5 more
TL;DR: The observations described above suggest that LT serves dual functions; it both attenuates accumulation of PMNs at sites of inflammation and impairs PMNs bactericidal activity against vegetative B. anthracis.
Journal ArticleDOI
Characterization of Monkeypox virus dissemination in the black-tailed prairie dog (Cynomys ludovicianus) through in vivo bioluminescent imaging.
Zachary P. Weiner,Johanna S. Salzer,Elizabeth LeMasters,James A. Ellison,Ashley V. Kondas,Clint N Morgan,Jeffery B Doty,Brock E. Martin,Panayampalli Subbian Satheshkumar,Victoria A. Olson,Christina L. Hutson +10 more
TL;DR: This study used recombinant MPXV containing the firefly luciferase gene (luc) and in vivo imaging technology to characterizeMPXV pathogenesis in the black-tailed prairie dog in real time and allowed for a greater understanding of how MPxV disseminates throughout the body in prairie dogs during the course of infection.