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Zahra Belhadjer
Researcher at University of Paris
Publications - 16
Citations - 1246
Zahra Belhadjer is an academic researcher from University of Paris. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 8 publications receiving 813 citations. Previous affiliations of Zahra Belhadjer include Necker-Enfants Malades Hospital & French Institute of Health and Medical Research.
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Journal ArticleDOI
Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic.
Zahra Belhadjer,Mathilde Meot,Fanny Bajolle,Diala Khraiche,Antoine Legendre,Samya Abakka,Johanne Auriau,Marion Grimaud,Mehdi Oualha,Maurice Beghetti,Julie Wacker,Caroline Ovaert,Sébastien Hascoët,Maëlle Selegny,Sophie Malekzadeh-Milani,Alice Maltret,Gilles Bosser,Nathan Giroux,Laurent Bonnemains,Jeanne Bordet,Sylvie Di Filippo,Pierre Mauran,Sylvie Falcon-Eicher,Jean Benoit Thambo,Bruno Lefort,Pamela Moceri,Lucile Houyel,Sylvain Renolleau,Damien Bonnet +28 more
TL;DR: Children may experience an acute cardiac decompensation caused by severe inflammatory state after SARS-CoV-2 infection and the multisystem inflammatory syndrome in children as defined by the US Centers for Disease Control and Prevention.
Journal ArticleDOI
Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemi
Zahra Belhadjer,Mathilde Meot,Fanny Bajolle,Diala Khraiche,Antoine Legendre,Samya Abakka,Johanne Auriau,Marion Grimaud,Mehdi Oualha,Maurice Beghetti,Julie Wacker,Caroline Ovaert,Sébastien Hascoët,Maëlle Selegny,Sophie Malekzadeh-Milani,Alice Maltret,Gilles Bosser,Nathan Giroux,Laurent Bonnemains,Jeanne Bordet,Sylvie Di Filippo,Pierre Mauran,Sylvie Falcon-Eicher,Jean-Benoit Thambo,Bruno Lefort,Pamela Moceri,Lucile Houyel,Sylvain Renolleau,Damien Bonnet +28 more
TL;DR: In this paper, a series of febrile pediatric patients with acute heart failure potentially associated with SARS-CoV-2 infection and the multisystem inflammatory syndrome in children as defined by the US Centers for Disease Control and Prevention were reported.
Journal ArticleDOI
Addition of Corticosteroids to Immunoglobulins Is Associated With Recovery of Cardiac Function in Multi-Inflammatory Syndrome in Children.
Zahra Belhadjer,Johanne Auriau,Mathilde Meot,Mehdi Oualha,Sylvain Renolleau,Lucile Houyel,Damien Bonnet,Damien Bonnet +7 more
Journal ArticleDOI
A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisystem inflammatory syndrome in children with severe myocarditis.
Camille de Cevins,Marine Luka,Marine Luka,Nikaïa Smith,Sonia Meynier,Aude Magérus,Francesco Carbone,Francesco Carbone,Victor Garcia-Paredes,Victor Garcia-Paredes,Laura Barnabei,Maxime Batignes,Alexandre Boullé,Marie-Claude Stolzenberg,Brieuc P. Perot,Bruno Charbit,Tinhinane Fali,Vithura Pirabarakan,Boris Sorin,Quentin Riller,Ghaith Abdessalem,Maxime Beretta,Ludivine Grzelak,Pedro Gonçalves,James P. Di Santo,Hugo Mouquet,Olivier Schwartz,Mohammed Zarhrate,Mélanie Parisot,Christine Bole-Feysot,Cécile Masson,Nicolas Cagnard,Aurélien Corneau,Camille Bruneau,Shen-Ying Zhang,Shen-Ying Zhang,Jean-Laurent Casanova,Jean-Laurent Casanova,Jean-Laurent Casanova,Brigitte Bader Meunier,Julien Haroche,Isabelle Melki,Isabelle Melki,Mathie Lorrot,Mehdi Oualha,Florence Moulin,Damien Bonnet,Zahra Belhadjer,Marianne Leruez,Slimane Allali,Christele Gras Leguen,Loïc de Pontual,Alain Fischer,Alain Fischer,Alain Fischer,Darragh Duffy,Frédéric Rieux-Laucat,Julie Toubiana,Julie Toubiana,Mickaël M. Ménager,Mickaël M. Ménager +60 more
TL;DR: The most severe forms of multisystem inflammatory syndrome in children related to SARS-CoV-2, that resulted in myocarditis, were characterized by elevated levels of pro-angiogenesis cytokines and several chemokines, and a weak response to type-I and type-II interferons, hyperinflammation and response to oxidative stress related to increased HIF-1α and VEGF signaling.
Journal ArticleDOI
A Monocyte/Dendritic Cell Molecular Signature of SARS-CoV-2 Related Multisystem Inflammatory Syndrome in Children (MIS-C) with Severe Myocarditis
Camille de Cevins,Marine Luka,Nikaïa Smith,Sonia Meynier,Aude Magérus,Francesco Carbone,Victor Garcia-Paredes,Laura Barnabei,Maxime Batignes,Alexandre Boullé,Marie-Claude Stolzenberg,Brieuc P. Perot,Bruno Charbit,Tinhinane Fali,Vithura Pirabarakan,Boris Sorin,Quentin Riller,Ghaith Abdessalem,Maxime Beretta,Ludivine Grzelak,Pedro Gonçalves,James P. Di Santo,Hugo Mouquet,Olivier Schwartz,Mohammed Zarhrate,Mélanie Parisot,Christine Bole-Feysot,Cécile Masson,Nicolas Cagnard,Aurélien Corneau,Camille Bruneau,Shen-Ying Zhang,Jean-Laurent Casanova,Brigitte Bader Meunier,Julien Haroche,Isabelle Melki,Mathie Lorrot,Mehdi Oualha,Florence Moulin,Damien Bonnet,Zahra Belhadjer,Mariane Leruez,Slimane Allali,Christele Gras Leguen,Loïc de Pontual,Alain Fischer,Darragh Duffy,Frédéric Rieux-Laucat,Julie Toubiana,Mickaël M. Ménager +49 more
TL;DR: A multi-parametric approach to the study of blood cells of 56 children hospitalized with suspicion of SARS-CoV-2 infection identified a unique monocyte/dendritic cell gene signature that correlated with the occurrence of severe myocarditis, characterized by sustained NF-κ B activity, TNF-α signaling, associated with decreased gene expression of NF-σ B inhibitors.