Z
Zane A. Brown
Researcher at University of Washington
Publications - 78
Citations - 6740
Zane A. Brown is an academic researcher from University of Washington. The author has contributed to research in topics: Pregnancy & Herpes simplex virus. The author has an hindex of 40, co-authored 78 publications receiving 6516 citations. Previous affiliations of Zane A. Brown include Boston Children's Hospital.
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Journal ArticleDOI
Genital herpes simplex virus infections: clinical manifestations, course, and complications.
TL;DR: The clinical course and complications of 268 patients with first episodes and 362 with recurrent episodes of genital herpes infection were reviewed, and the major concerns were the frequency of recurrences and fear of transmitting infection to partners or infants.
Journal ArticleDOI
The acquisition of herpes simplex virus during pregnancy
Zane A. Brown,S Selke,Judy Zeh,Jerome Kopelman,Maslow A,Rhoda Ashley,D H Watts,Sylvia Berry,Herd M,Lawrence Corey +9 more
TL;DR: In this article, the authors studied 7046 pregnant women whom serologic tests showed to be at risk for genital herpes simplex virus (HSV) infection, and found that women who were initially seronegative for both HSV-1 and HSV2 had an estimated chance of seroconversion for either virus of 3.7 percent; those wh...
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Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant.
TL;DR: Neonatal HSV infection rates can be reduced by preventing maternal acquisition of genital HSV-1 andHSV-2 infection near term and limiting the use of invasive monitors among women shedding HSV at the time of labor.
Journal ArticleDOI
Neonatal herpes simplex virus infection in relation to asymptomatic maternal infection at the time of labor
Zane A. Brown,Jacqueline Benedetti,Rhoda Ashley,Sandra K. Burchett,Stacy Selke,Sylvia Berry,Louis A. Vontver,Lawrence Corey +7 more
TL;DR: Pregnant women in early labor who were without symptoms or signs of genital HSV infection were prospectively obtained HSV cultures from the cervix and external genitalia to define the risk factors associated with neonatal acquisition of herpes simplex virus (HSV) infection.
Journal ArticleDOI
Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant
TL;DR: No data exist on whether cesarean delivery, the standard of care for women with genital herpes lesions at the time of delivery, reduces HSV transmission, but neonatal HSV infection rates can be reduced by preventing maternal acquisition of genital HSV-1 andHSV-2 infection near term.